Five Years of siRNA Delivery: Spotlight on Gold Nanoparticles

Authors

  • Abigail K. R. Lytton-Jean,

    1. H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
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  • Robert Langer,

    1. H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Biology, Massachusetts Institute of Technology, Cambridge MA, USA
    3. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA
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  • Daniel G. Anderson

    Corresponding author
    1. H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Biology, Massachusetts Institute of Technology, Cambridge MA, USA
    3. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA, USA
    • H Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
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Abstract

Gold nanoparticles have become widely used in scientific research due to their unique physical and chemical properties. In the last several years their use as siRNA delivery agents has been investigated. Here, progress made using gold nanoparticles for siRNA delivery is described and the different strategies employed are compared.

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