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Keywords:

  • leucine-enkephalin;
  • nanostructures;
  • curcumin;
  • encapsulation;
  • responsive materials
Thumbnail image of graphical abstract

An opioid (leucine-enkephalin) conformational analogue forms diverse nanostructures such as vesicles, tubes, and organogels through self-assembly. The nanovesicles encapsulate the natural hydrophobic drug curcumin and allow the controlled release through cation-generated porogens in membrane mimetic solvent.