Fireflies-On-A-Chip: (Ionic Liquid)–Aqueous Microdroplets for Biphasic Chemical Analysis

Authors

  • Zahra Barikbin,

    1. Singapore-MIT Alliance, National University of Singapore, 4 Engineering Drive 3, E4-04-10, 117576, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Md. Taifur Rahman,

    1. Singapore-MIT Alliance, National University of Singapore, 4 Engineering Drive 3, E4-04-10, 117576, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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    • School of Chemistry and Chemical Engineering, The Queen's University of Belfast, Belfast, BT9 5AG, United Kingdom

  • Saif A. Khan

    Corresponding author
    1. Singapore-MIT Alliance, National University of Singapore, 4 Engineering Drive 3, E4-04-10, 117576, Singapore
    2. Department of Chemical and Bimolecular Engineering, National University of Singapore, 4 Engineering Drive 4, 117576, Singapore
    • Singapore-MIT Alliance, National University of Singapore, 4 Engineering Drive 3, E4-04-10, 117576, Singapore.
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Abstract

original image

Inspired by the enchanting bioluminescence of fireflies, herein microfluidic droplet-based ‘fireflies’ for non-invasive biphasic chemical analysis are demonstrated. Bicompartmental droplets are created where a model analyte is transported from the aqueous compartment to the adjacent ionic liquid segment, yielding a bright fluid firefly structure via a localized catalytic reaction. Analysis of fluorescence emission kinetics and a method to passively decouple the two compartments at a constriction are presented.

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