Gold Nanoparticles: Colorimetric Detection of HIV-1 Ribonuclease H Activity by Gold Nanoparticles (Small 10/2011)

Authors

  • Xiaoji Xie,

    1. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
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  • Wei Xu,

    1. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
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  • Tianhu Li,

    1. Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
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  • Xiaogang Liu

    Corresponding author
    1. Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore
    2. Institute of Materials Research and Engineering, 3, Research Link, Singapore 117602, Singapore
    • Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
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Abstract

original image

The frontispiece of the Communications section (middle) features a low-cost and convenient approach to the colorimetric detection of HIV-1 ribonuclease H activity using unmodified gold nanoparticles. The method is potentially useful for screening enzyme inhibitors in drug discovery. For more information, please read the Communication “Colorimetric Detection of HIV-1 Ribonuclease H Activity by Gold Nanoparticles,” by X. Liu and co-workers, beginning on page 1392.

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