Flake-Shell Capsules: Adjustable Inorganic Structures

Authors

  • Qingmin Ji,

    Corresponding author
    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
    • World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan.
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  • Chunyan Guo,

    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
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  • Xiaoyan Yu,

    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
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  • Christopher J. Ochs,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • Jonathan P. Hill,

    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
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  • Frank Caruso,

    1. Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia
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  • Hiromoto Nakazawa,

    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
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  • Katsuhiko Ariga

    Corresponding author
    1. World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
    • World Premier International (WPI), Research Center for Materials Nanoarchitectonics (MANA) and JST, CREST, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan.
    Search for more papers by this author

Abstract

original image

Structure-adjustable capsules are fabricated from inorganic components by using a self-template dissolution–regrowth mechanism to give flake-shell silica microcapsules. The capsules shrink under thermal stimulus and their structures can be adjusted by treatment at different pH values. Tuning of shell pore diameters leads to tailored drug release over prolonged periods.

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