CdSe Quantum Dots Enhance Electrical and Electrochemical Signals of Nanogap Devices for Bioanalysis

Authors

  • Yang Yu,

    1. Research Center for Biomimetic Functional, Materials and Sensing Devices, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China
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  • Xing Chen,

    1. Research Center for Biomimetic Functional, Materials and Sensing Devices, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China
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  • Yan Wei,

    1. Department of Chemistry, Wannan Medical College, Wuhu 241002, PR China
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  • Jin-Huai Liu,

    1. Research Center for Biomimetic Functional, Materials and Sensing Devices, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China
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  • Shu-Hong Yu,

    1. Department of Chemistry, University of Science and Technology of China, Hefei 230026, PR China
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  • Xing-Jiu Huang

    Corresponding author
    1. Research Center for Biomimetic Functional, Materials and Sensing Devices, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China
    • Research Center for Biomimetic Functional, Materials and Sensing Devices, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China.
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Abstract

original image

CdSe quantum dot-labeled streptavidin (CdSe QD–SAv) is introduced into nanogap to amplify the current and impedimetric signals generated in a biosensor for detecting the biotin–streptavidin binding event by electrical and electrochemical measurements.

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