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Keywords:

  • nanoparticles;
  • protein–polymer conjugates;
  • albumin;
  • poly(methyl methacrylate);
  • drug delivery
Thumbnail image of graphical abstract

Amphiphilic bovine serum albumin-poly(methyl methacrylate) conjugate forms nanoparticles with the uniform size of ∼100 nm by self-assembling. Loaded with the hydrophobic anti-tumor drug camptothecin, the nanoparticle efficiently delivers drugs into cancer cells, and thus inhibits ∼79% of tumor growth in animals compared with free drug.