Thin, Flexible Sensors and Actuators as ‘Instrumented’ Surgical Sutures for Targeted Wound Monitoring and Therapy

Authors

  • Dae-Hyeong Kim,

    1. School of Chemical and Biological Engineering, WCU Program of Chemical Convergence for Energy and Environment, Institute of Chemical Processes, Inter-University Semiconductor Research Center, Seoul National University, Seoul 151-741, Republic of Korea
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  • Shuodao Wang,

    1. Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
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  • Hohyun Keum,

    1. Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
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  • Roozbeh Ghaffari,

    1. MC10 Inc., 36 Cameron Avenue, Cambridge, MA 02140, USA
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  • Yun-Soung Kim,

    1. Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
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  • Hu Tao,

    1. Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA
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  • Bruce Panilaitis,

    1. Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA
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  • Ming Li,

    1. State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, Dalian 116024, China
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  • Zhan Kang,

    1. State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, Dalian 116024, China
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  • Fiorenzo Omenetto,

    1. Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA
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  • Yonggang Huang,

    1. Department of Mechanical Engineering and Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA
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  • John A. Rogers

    Corresponding author
    1. Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
    • Department of Materials Science and Engineering, Beckman Institute for Advanced Science and Technology and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
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Abstract

original image

Proper healing of incised skin is critical to the natural processes of tissue repair. Concepts in flexible silicon electronics enable integration of actuators, sensors and a variety of semiconductor devices onto thin strips of plastic or biopolymers, to yield ‘instrumented’ suture threads for monitoring and accelerating the wound healing in this context. Bifacial systems of this type demonstrate various classes of functionality, in live animal models. Detailed modelling of the mechanics reveals stress and strain distributions in such applications, to support design strategies for robust operation.

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