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Microfluidics for Manipulating Cells

Authors

  • Xuan Mu,

    1. Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China
    2. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, PR China
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  • Wenfu Zheng,

    1. Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China
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  • Jiashu Sun,

    1. Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China
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  • Wei Zhang,

    1. Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China
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  • Xingyu Jiang

    Corresponding author
    1. Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China
    • Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for NanoScience and Technology, No. 11, Beiyitiao, ZhongGuanCun, Beijing 100190, PR China.
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Errata

This article is corrected by:

  1. Errata: Corrigendum: Microfluidics for Manipulating Cells Volume 9, Issue 7, 969, Article first published online: 2 April 2013

Abstract

Microfluidics, a toolbox comprising methods for precise manipulation of fluids at small length scales (micrometers to millimeters), has become useful for manipulating cells. Its uses range from dynamic management of cellular interactions to high-throughput screening of cells, and to precise analysis of chemical contents in single cells. Microfluidics demonstrates a completely new perspective and an excellent practical way to manipulate cells for solving various needs in biology and medicine. This review introduces and comments on recent achievements and challenges of using microfluidics to manipulate and analyze cells. It is believed that microfluidics will assume an even greater role in the mechanistic understanding of cell biology and, eventually, in clinical applications.

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