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Communication

Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking

  1. Sarit S. Agasti1,
  2. Rainer H. Kohler1,
  3. Monty Liong1,
  4. Vanessa M. Peterson1,
  5. Hakho Lee1,
  6. Ralph Weissleder1,2,*

Article first published online: 21 SEP 2012

DOI: 10.1002/smll.201201007

Issue

Small

Small

Volume 9, Issue 2, pages 222–227, January 28, 2013

Additional Information

How to Cite

Agasti, S. S., Kohler, R. H., Liong, M., Peterson, V. M., Lee, H. and Weissleder, R. (2013), Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking. Small, 9: 222–227. doi: 10.1002/smll.201201007

Author Information

  1. 1

    Center for Systems Biology, Massachusetts General Hospital/Harvard, Medical School, 185 Cambridge St., Boston, MA 02114, USA

  2. 2

    Department of Systems Biology, Harvard Medical School, 200 Longwood Ave., Alpert 536, Boston, MA 02115, USA

*Center for Systems Biology, Massachusetts General Hospital/Harvard, Medical School, 185 Cambridge St., Boston, MA 02114, USA.

Publication History

  1. Issue published online: 21 JAN 2013
  2. Article first published online: 21 SEP 2012
  3. Manuscript Revised: 22 JUN 2012
  4. Manuscript Received: 9 MAY 2012

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Keywords:

  • photoactivation;
  • nanoprobes;
  • cell labeling;
  • targeting;
  • biomarkers
Thumbnail image of graphical abstract

A photoactivated nanoprobe for cell labeling and tracking is demonstrated. The nanoprobe enables all targeted cells to be imaged (at 680 nm) as well as specific cells to be photoactivated using 405 nm light. Photoactivated cells can then be tracked (at 525 nm) spatiotemporally in a separate channel over prolonged periods.

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