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Communication

NIR-Triggered Release of Caged Nitric Oxide using Upconverting Nanostructured Materials

  1. John V. Garcia1,2,
  2. Jianping Yang1,
  3. Dengke Shen1,
  4. Chi Yao1,
  5. Xiaoming Li1,
  6. Rui Wang1,
  7. Galen D. Stucky2,*,
  8. Dongyuan Zhao1,*,
  9. Peter C. Ford2,*,
  10. Fan Zhang1,*

Article first published online: 25 JUL 2012

DOI: 10.1002/smll.201201213

Issue

Small

Small

Volume 8, Issue 24, pages 3800–3805, December 21, 2012

Additional Information

How to Cite

Garcia, J. V., Yang, J., Shen, D., Yao, C., Li, X., Wang, R., Stucky, G. D., Zhao, D., Ford, P. C. and Zhang, F. (2012), NIR-Triggered Release of Caged Nitric Oxide using Upconverting Nanostructured Materials. Small, 8: 3800–3805. doi: 10.1002/smll.201201213

Author Information

  1. 1

    Department of Chemistry and Laboratory of Advanced Materials, Fudan University, Shanghai 200433, PR China

  2. 2

    Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, 93106 USA

*Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, 93106 USA

Publication History

  1. Issue published online: 15 DEC 2012
  2. Article first published online: 25 JUL 2012
  3. Manuscript Received: 1 JUN 2012

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Keywords:

  • upconversion;
  • nanomaterials;
  • NIR-triggered release;
  • caged nitric oxides;
  • photoactivation
Thumbnail image of graphical abstract

Lanthanide-doped upconversion nanoparticles (UCNPs) mediate nitric oxide uncaging from Roussin's black salt anion Fe4S3(NO)7− using NIR light from a simple diode laser operating continuously at 980 nm. This result offers a new paradigm for applications of multi-photon absorption in the therapeutic delivery of NO.

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