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Keywords:

  • gold nanoparticles;
  • biosensing;
  • nanoprobes;
  • DNA;
  • nanodumbbells
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Nanodumbbell gold nanoparticle (AuNP) dimers connected by DNA show significant change in interparticle distance in the presence of a specific analyte, ATP. The nanodumbbell begins in an extended state, but after the addition of the analyte, the DNA connecting the AuNPs forms a stable hairpin, which causes a large decrease in the interparticle distance.