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Keywords:

  • chemical design;
  • iron oxide nanoparticles;
  • biocompatibility;
  • toxicity;
  • nanomedicine

Abstract

Iron oxide nanoparticles are one of the most versatile and safe nanomaterials used in medicine. Recent progress in nanochemistry enables fine control of the size, crystallinity, uniformity, and surface properties of iron oxide nanoparticles. In this review, the synthesis of chemically designed biocompatible iron oxide nanoparticles with improved quality and reduced toxicity is discussed for use in diverse biomedical applications.