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A Simple Route to Prepare Monodisperse Au NP-Decorated, Dye-doped, Superparamagnetic Nanocomposites for Optical, MR, and CT Trimodal Imaging

Authors

  • Wenjie Dong,

    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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  • Yongsheng Li,

    Corresponding author
    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
    • Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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  • Dechao Niu,

    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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  • Zhi Ma,

    1. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
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  • Xiaohang Liu,

    1. Department of Radiology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China
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  • Jinlou Gu,

    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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  • Wenru Zhao,

    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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  • Yuanyi Zheng,

    Corresponding author
    1. Second Affiliated Hospital of Chongqing, Medical University Chongqing 400010, China
    • Second Affiliated Hospital of Chongqing, Medical University Chongqing 400010, China.
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  • Jianlin Shi

    Corresponding author
    1. Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
    2. The State Key Laboratory of High Performance, Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
    • Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China
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Abstract

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Monodisperse and uniform AuNP-decorated, dye-doped, superparamagnetic nanocomposites (Fe3O4@dye-hybrid@Au) are fabricated by using a simple method in which the Au NP formation and their attachment onto the core surface via S–Au covalent bonds proceeds almost simultaneously in a one-pot synthesis. The as-synthesized nanocomposites can simultaneously enhance the contrast effects for MR, CT, and cellular-sensitive optical imaging.

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