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Keywords:

  • sperm exhaustion;
  • biodesign;
  • sperm sorting;
  • microfluidic sorting;
  • fertility
Thumbnail image of graphical abstract

Fertilization is central to the survival and propagation of a species, however, the precise mechanisms that regulate the sperm's journey to the egg are not well understood. In nature, the sperm has to swim through the cervical mucus, akin to a microfluidic channel. Inspired by this, a simple, cost-effective microfluidic channel is designed on the same scale. The experimental results are supported by a computational model incorporating the exhaustion time of sperm.