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Keywords:

  • dityrosine;
  • self-fluorescent;
  • cross-link;
  • encapsulation;
  • label-free imaging
Thumbnail image of graphical abstract

Cross-linked, self-fluorescent Au nanoparticle/polypeptide nanocapsules comprising dityrosine are prepared by the self-assembly of the random copolypeptides comprising L-lysine and L-tyrosine upon subsequent cross-linking of tyrosine residues by chloroaurate reduction. These nanocapsules are demonstrated be useful as encapsulants for protein encapsulation and as optical probes for label-free cell imaging. The reduction process is so mild that the protein can still retain its function.