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Polymer Particles: Biomimetic Methodology to Produce Polymeric Multilayered Particles for Biotechnological and Biomedical Applications (Small 15/2013)

Authors

  • Ana Catarina Lima,

    1. 3B's Research Group–Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, Zona Industrial da Gandra, S. Claudio do Barco, 4806-909 Caldas das Taipas, Giomarães, Portugal
    2. ICVC/3B's–PT Government Associate Laboratory, Braga/Guimarães, Portugal
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  • Catarina A. Custódio,

    1. 3B's Research Group–Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, Zona Industrial da Gandra, S. Claudio do Barco, 4806-909 Caldas das Taipas, Giomarães, Portugal
    2. ICVC/3B's–PT Government Associate Laboratory, Braga/Guimarães, Portugal
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  • Carmen Alvarez-Lorenzo,

    1. Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain
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  • João F. Mano

    Corresponding author
    1. 3B's Research Group–Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, Zona Industrial da Gandra, S. Claudio do Barco, 4806-909 Caldas das Taipas, Giomarães, Portugal
    2. ICVC/3B's–PT Government Associate Laboratory, Braga/Guimarães, Portugal
    • 3B's Research Group–Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, Zona Industrial da Gandra, S. Claudio do Barco, 4806-909 Caldas das Taipas, Giomarães, Portugal.
    Search for more papers by this author

Abstract

original image

Multicompartmentalized particles are envisioned to offer the simultaneous release of various bioactive agents with different kinetics and to be able to encapsulate cells in order to fulfill therapeutic demands. Inspired by the rolling of water droplets on lotus leafs, J. F. Mano and co-workers present a biomimetic methodology on page 2487 that is based on superhydrophobic surfaces in order to construct multilayered polymeric systems, adding sequential layers such that molecules or cells may be separately confined in compartments with high efficiency.

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