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Keywords:

  • water-soluble polythiophene;
  • polymersomes;
  • vesicular compartments;
  • ATP sensor;
  • enzymatic reactions
Thumbnail image of graphical abstract

Polymersomes are encapsulated with a fluorescent reporter and a non-labeled enzyme for sensing of adenosine triphosphate (ATP). As B. Liedberg and co-workers report on page 442, passive diffusion of exogenously added ATP through the membrane is sensed by monitoring the ATPinduced fluorescence quenching of the reporter polymer followed by partial recovery of its emission due to hydrolysis of reporter-bound ATP by alkaline phosphatase.