Small

Cover image for Vol. 7 Issue 16

August 22, 2011

Volume 7, Issue 16

Pages 2265–2400

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Optical Antennas: Plasmonic Nickel Nanoantennas (Small 16/2011) (page 2265)

      Jianing Chen, Pablo Albella, Zhaleh Pirzadeh, Pablo Alonso-González, Florian Huth, Stefano Bonetti, Valentina Bonanni, Johan Åkerman, Josep Nogués, Paolo Vavassori, Alexandre Dmitriev, Javier Aizpurua and Rainer Hillenbrand

      Article first published online: 16 AUG 2011 | DOI: 10.1002/smll.201190056

      Thumbnail image of graphical abstract

      The cover shows the near-field amplitude image of dipolar plasmon modes in nickel nanodisks. Each disk exhibits two bright spots oscillating along the polarization direction of the incident light, revealing the enhanced near-field at the rims of the nickel disks. The image was recorded by a scattering-type scanning near-field microscope (s-SNOM) within a study of the optical and magnetic properties of nickel nanostructures. An interesting dual functionality is observed: a strong magnetic behavior is identified together with a clear plasmonic response, which could be a useful building block for future biotechnological and optoelectronic applications, where active control of the functional components is required. For more information, please read the Full Paper “Plasmonic Nickel Nanoantennas” by R. Hillenbrand and co-workers, beginning on page 2341.

  2. Inside Front Cover

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Adhesive Microstructures: Anisotropic Adhesion Properties of Triangular-Tip-Shaped Micropillars (Small 16/2011) (page 2266)

      Moon Kyu Kwak, Hoon Eui Jeong, Won Gyu Bae, Ho-Sup Jung and Kahp Y. Suh

      Article first published online: 16 AUG 2011 | DOI: 10.1002/smll.201190057

      Thumbnail image of graphical abstract

      The cover image illustrates the anisotropic adhesion property of triangular-tip-shaped micropillars, which are proposed as a new design for bio-inspired adhesive structures. These unique micropillars show directional shear adhesion with respect to the change of peeling direction (8.8–17.2 J m−2) as well as relatively high normal adhesion (8.2–10 N m−2). The directional adhesion is ascribed to the propagation line of cracks under triangular contact domains. When cracks initiate from the vertex, they can easily propagate to the inner region, resulting in relatively lower shear adhesion. In contrast, when peeled from the side of the triangle, the cracks form a pseudoline contact, and thus the crack propagation is retarded. For more information, please read the Communication “Anisotropic Adhesion Properties of Triangular-Tip-Shaped Micropillars” by K. Y. Suh and co-workers, beginning on page 2296.

  3. Contents

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Contents: (Small 16/2011) (pages 2267–2272)

      Article first published online: 16 AUG 2011 | DOI: 10.1002/smll.201190058

  4. Review

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Chemically Functionalized Surface Patterning (pages 2273–2289)

      Xiaozhu Zhou, Freddy Boey, Fengwei Huo, Ling Huang and Hua Zhang

      Article first published online: 16 JUN 2011 | DOI: 10.1002/smll.201002381

      Thumbnail image of graphical abstract

      Patterning substrates with versatile chemical functionalities from micro- to nanometer scale is a long-standing and interesting topic. In this review, a variety of methods are introduced for patterning small molecules, biomolecules, polymers, and nanoparticles.

  5. Frontispiece

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Cancer Therapy: Single-Cell-Level Microplasma Cancer Therapy (Small 16/2011) (page 2290)

      Jae Young Kim, Yanzhang Wei, Jinhua Li, Paul Foy, Thomas Hawkins, John Ballato and Sung-O Kim

      Article first published online: 16 AUG 2011 | DOI: 10.1002/smll.201190059

      Thumbnail image of graphical abstract

      The image shows the apoptotic response in B16F0 tumor cells induced by a 15 μm hollow-core optical fiber microplasma jet assay using the TUNEL assay, which detects DNA nicks–an important cell apoptotic indicator. Apoptotic tumor cells treated by the plasma device show DNA nicks, and their nuclei are dyed to a bright color by the imaging assay kit, whereas no response was found in untreated cells. A well-defined boundary between plasma-treated and nontreated areas can be observed. This work enables new directed cancer therapies based on a highly flexible and precise hollow, optical-fiber-based microplasma cancer endoscope, and it offers unique advantages to understanding plasmainduced tumor cell apoptosis.

  6. Communications

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Single-Cell-Level Microplasma Cancer Therapy (pages 2291–2295)

      Jae Young Kim, Yanzhang Wei, Jinhua Li, Paul Foy, Thomas Hawkins, John Ballato and Sung-O Kim

      Article first published online: 10 JUN 2011 | DOI: 10.1002/smll.201100456

      Thumbnail image of graphical abstract

      A flexible microplasma endoscope based on a 15 μm hollow-core glass optical fiber is fabricated, and tumor cell apoptotic analysis supports its potential use in targeted cancer therapies. The optical-fiber microplasma jet reveals antitumor activity at a certain plasma dose in animal studies.

    2. Anisotropic Adhesion Properties of Triangular-Tip-Shaped Micropillars (pages 2296–2300)

      Moon Kyu Kwak, Hoon Eui Jeong, Won Gyu Bae, Ho-Sup Jung and Kahp Y. Suh

      Article first published online: 1 JUN 2011 | DOI: 10.1002/smll.201100455

      Thumbnail image of graphical abstract

      Directional dry adhesive microstructures consisting of high-density triangular-tip-shaped micropillars are described. The wide-tip structures allow for unique directional shear adhesion properties with respect to the peeling direction, along with relatively high normal adhesion.

    3. Addressing Brain Tumors with Targeted Gold Nanoparticles: A New Gold Standard for Hydrophobic Drug Delivery? (pages 2301–2306)

      Yu Cheng, Joseph D. Meyers, Richard S. Agnes, Tennyson L. Doane, Malcolm E. Kenney, Ann-Marie Broome, Clemens Burda and James P. Basilion

      Article first published online: 1 JUN 2011 | DOI: 10.1002/smll.201100628

      Thumbnail image of graphical abstract

      EGF-modified Au NP–Pc 4 conjugates showed 10-fold improved selectivity to the brain tumor compared to untargeted conjugates. The hydrophobic photodynamic therapy drug Pc 4 can be delivered efficiently into glioma brain tumors by EGF peptide-targeted Au NPs. Compared to the untargeted conjugates, EGF–Au NP–Pc 4 conjugates showed 10-fold improved selectivity to the brain tumor. This delivery system holds promise for future delivery of a wider range of hydrophobic therapeutic drugs for the treatment of hard-to-reach cancers.

    4. Facile Synthesis of Gold Nanorice Enclosed by High-Index Facets and Its Application for CO Oxidation (pages 2307–2312)

      Yiqun Zheng, Jing Tao, Hongyang Liu, Jie Zeng, Taekyung Yu, Yanyun Ma, Christine Moran, Lijun Wu, Yimei Zhu, Jingyue Liu and Younan Xia

      Article first published online: 1 JUN 2011 | DOI: 10.1002/smll.201100106

      Thumbnail image of graphical abstract

      A facile method for generating Au nanorice enclosed by high-index facets in high purity. The nanorice shows much higher catalytic activity for CO oxidation than multiply twinned particles of Au enclosed by {111} facets at temperatures below 300 °C.

    5. Carbon-Nanotube Through-Silicon Via Interconnects for Three-Dimensional Integration (pages 2313–2317)

      Teng Wang, Kejll Jeppson, Lilei Ye and Johan Liu

      Article first published online: 21 JUN 2011 | DOI: 10.1002/smll.201100615

      Thumbnail image of graphical abstract

      Interconnection of carbon-nanotube (CNT)-filled through-silicon vias is demonstrated through an easy-to-implement process based on mechanical fastening. Direct CNT-to-CNT and CNT-to-Au contacts are realized at the microscale, and their specific contact resistances extracted from electrical measurements are approximately 1.2 × 10−3 Ω cm2 and 4.5 × 10−4 Ω cm2, respectively.

  7. Full Papers

    1. Top of page
    2. Cover Picture
    3. Inside Front Cover
    4. Contents
    5. Review
    6. Frontispiece
    7. Communications
    8. Full Papers
    1. Patterning Nanostructured, Synthetic, Polymeric Receptors by Simultaneous Projection Photolithography, Nanomolding, and Molecular Imprinting (pages 2318–2325)

      Ana V. Linares, Aude Falcimaigne-Cordin, Levi A. Gheber and Karsten Haupt

      Article first published online: 21 JUN 2011 | DOI: 10.1002/smll.201100248

      Thumbnail image of graphical abstract

      Fast microfabrication of molecularly imprinted polymer dot arrays can be achieved via microscope projection photolithography. When imprinted with fluorescein or with myoglobin, binding studies and fluorescence microscopy reveal that the fluorescence signal greatly increases for dots composed of polymer nanofilaments compared to plain dots. Such nanostructured microarrays of synthetic receptors have a great potential for biochips.

    2. Self-Organization of Thin Polymer Films Guided by Electrostatic Charges on the Substrate (pages 2326–2333)

      Dan Zhao, Aaron D. Martinez, Xiaolei Xi, Xinlei Ma, Ning Wu and Tingbing Cao

      Article first published online: 3 JUN 2011 | DOI: 10.1002/smll.201100245

      Thumbnail image of graphical abstract

      A thin polymer film is spin-coated onto a topographically flat substrate where electrostatic charges are prepatterned and embedded permanently. The spatially patterned charges cause a lateral gradient of the electrostatic stress at the polymer–air interface, which drives polymer flow into periodic arrays.

    3. Measurement of the Intrinsic Thermal Conductivity of a Multiwalled Carbon Nanotube and Its Contact Thermal Resistance with the Substrate (pages 2334–2340)

      Juekuan Yang, Yang Yang, Scott W. Waltermire, Timothy Gutu, Alfred A. Zinn, Terry T. Xu, Yunfei Chen and Deyu Li

      Article first published online: 7 JUN 2011 | DOI: 10.1002/smll.201100429

      Thumbnail image of graphical abstract

      Through multiple measurements of the same carbon nanotube, the intrinsic thermal conductivity of the tube and the contact thermal resistance between the tube and its substrate are extracted. The derived intrinsic thermal conductivity is significantly higher than the effective ones from a single measurement.

    4. Plasmonic Nickel Nanoantennas (pages 2341–2347)

      Jianing Chen, Pablo Albella, Zhaleh Pirzadeh, Pablo Alonso-González, Florian Huth, Stefano Bonetti, Valentina Bonanni, Johan Åkerman, Josep Nogués, Paolo Vavassori, Alexandre Dmitriev, Javier Aizpurua and Rainer Hillenbrand

      Article first published online: 16 JUN 2011 | DOI: 10.1002/smll.201100640

      Thumbnail image of graphical abstract

      Experimental evidence of plasmon resonances in pure nickel nanoantennas is provided by both far-field spectroscopy and near-field microscopy. Ultra-high resolution near-field microscopy visualizes the dipole plasmon modes in nickel disks as well as the transverse plasmon mode of elongated nickel nanoantennas. The shifts between far- and near-field spectra of plasmonic antennas are also elucidated, which points out the need of taking into account both near- and far-field properties when designing nanophotonic devices.

    5. Quantification of Uptake and Localization of Bovine Serum Albumin-Stabilized Single-Wall Carbon Nanotubes in Different Human Cell Types (pages 2348–2355)

      Brian D. Holt, Kris Noel Dahl and Mohammad F. Islam

      Article first published online: 31 MAY 2011 | DOI: 10.1002/smll.201100437

      Thumbnail image of graphical abstract

      Single-wall carbon nantoubes are individually dispersed at high yield by bovine serum albumin. The nanotubes are biocompatible and are readily uptaken into human mesenchymal stem cells and human cancer cells. It is shown via Raman spectroscopy and cell imaging that the nanotubes are preferentially located intracellularly in quite high concentrations. This platform allows for biologically relevant, high-concentration nanotube applications.

    6. Separation of Chemical Reaction Intermediates by Metal–Organic Frameworks (pages 2356–2364)

      Andrea Centrone, Erik E. Santiso and T. Alan Hatton

      Article first published online: 31 MAY 2011 | DOI: 10.1002/smll.201100098

      Thumbnail image of graphical abstract

      The separation of four intermediates and byproducts found in the commercial synthesis of an active pharmaceutical ingredient is achieved using an HPLC column packed with a metal–organic framework material (ZIF-8). The interplay between the thermodynamic driving force for the solute adsorption within the framework pores and the kinetics for solute diffusion into the pores is found to drive the separation.

    7. Self-Assembled Large Au Nanoparticle Arrays with Regular Hot Spots for SERS (pages 2365–2371)

      Aiqing Chen, A. Eugene DePrince III, Arnaud Demortière, Alexandra Joshi-Imre, Elena V. Shevchenko, Stephen K. Gray, Ulrich Welp and Vitalii K. Vlasko-Vlasov

      Article first published online: 1 JUN 2011 | DOI: 10.1002/smll.201100686

      Thumbnail image of graphical abstract

      The cost-effective self-assembly of 80 nm Au nanoparticles into well-ordered varrays, which exhibit specific optical resonances due to strong interparticle coupling, is demonstrated. A photoluminescence enhancement 3–5 times larger than those previously reported is shown. An estimate of the surface-enhanced Raman spectroscopy electromagnetic enhancement factor of 104 is obtained by correlating Raman signals with high-resolution microscopy images of quantum dots on Au arrays and of 108 for benzenethiol molecules at larger excitation wavelengths.

    8. Wrapping Graphene Sheets Around Organic Wires for Making Memory Devices (pages 2372–2378)

      Shuai Wang, Kiran Kumar Manga, Meng Zhao, Qiaoliang Bao and Kian Ping Loh

      Article first published online: 21 JUN 2011 | DOI: 10.1002/smll.201100426

      Thumbnail image of graphical abstract

      A simple method to synthesize hybrid materials containing 1D organic wires and 2D graphene oxide (GO) consists of sonicating tetracene and GO together in diluted fuming HNO3. The GO–organic wire hybrids are used to fabricate memory devices that exhibit electrical bistability.

    9. Direct Manipulation of a Single Potassium Channel Gate with an Atomic Force Microscope Probe (pages 2379–2383)

      Mitsunori Kitta, Toru Ide, Minako Hirano, Hiroyuki Tanaka, Toshio Yanagida and Tomoji Kawai

      Article first published online: 8 JUN 2011 | DOI: 10.1002/smll.201002337

      Thumbnail image of graphical abstract

      An atomic force microscope is used to apply a mechanical stimulus to a potassium channel protein, and its gating is monitored in real time. The channel-open probability increases greatly when pushing the cytoplasmic domain toward the membrane. This provides direct evidence of coupling between conformational changes in the cytoplasmic domain and channel gating.

    10. On the Lifecycle of Nanocomposites: Comparing Released Fragments and their In-Vivo Hazards from Three Release Mechanisms and Four Nanocomposites (pages 2384–2395)

      Wendel Wohlleben, Sandra Brill, Matthias W. Meier, Michael Mertler, Gerhard Cox, Sabine Hirth, Bernhard von Vacano, Volker Strauss, Silke Treumann, Karin Wiench, Lan Ma-Hock and Robert Landsiedel

      Article first published online: 14 JUN 2011 | DOI: 10.1002/smll.201002054

      Thumbnail image of graphical abstract

      The human hazard emerging from released fragments is studied in vivo, and no differences due to the presence of the nanofillers are indicated. Normal use versus do-it-yourself versus weathering are compared, as well as carbon nanotubes versus nanoparticle fillers, polymer versus inorganic matrices. Among these 12 scenarios, surface-structured fragments were found, but only in one case the degradation was significantly changed by the nanofiller.

    11. Scanning Tunneling Luminescence of Individual CdSe Nanowires (pages 2396–2400)

      Theresa Lutz, Alexander Kabakchiev, Thomas Dufaux, Christian Wolpert, Zhe Wang, Marko Burghard, Klaus Kuhnke and Klaus Kern

      Article first published online: 16 JUN 2011 | DOI: 10.1002/smll.201100434

      Thumbnail image of graphical abstract

      Local light generation in freestanding semiconductor nanowires (NWs) is enabled via scanning tunneling luminescence spectroscopy through the direct injection of holes and electrons without the need for plasmonic coupling. The luminescence spectra of individual CdSe NWs obtained by localized charge injection by the metal tip are discussed with respect to their shape and their dependence on the NW diameter. A model for the underlying light excitation mechanism is proposed.

SEARCH

SEARCH BY CITATION