Antioxidant Deactivation on Graphenic Nanocarbon Surfaces (pages 2775–2785)
Xinyuan Liu, Sujat Sen, Jingyu Liu, Indrek Kulaots, David Geohegan, Agnes Kane, Alex A. Puretzky, Christopher M. Rouleau, Karren L. More, G. Tayhas R. Palmore and Robert H. Hurt
Article first published online: 5 AUG 2011 | DOI: 10.1002/smll.201100651
Oxygen reacts with active sites on graphenic carbon surfaces to produce surface-bound oxygen intermediates that react heterogeneously with the antioxidant glutathione to restore the carbon surface and complete a catalytic cycle. This catalytic reaction is seen for a wide range of graphenic carbon materials and may contribute to oxidative stress pathways in nanotoxicity.