Nanodevices: Location of Biomarkers and Reagents within Agarose Beads of a Programmable Nano-bio-chip (Small 5/2011) (page 612)
Jesse V. Jokerst, Jie Chou, James P. Camp, Jorge Wong, Alexis Lennart, Amanda A. Pollard, Pierre N. Floriano, Nicolaos Christodoulides, Glennon W. Simmons, Yanjie Zhou, Mehnaaz F. Ali and John T. McDevitt
Article first published online: 2 MAR 2011 | DOI: 10.1002/smll.201190015
The frontispiece features a diagnostic assay that can operate at the point-of-need. In spite of their ultrasmall size and inexpensive cost, these nanodevice sensor ensembles exhibit excellent performance characteristics and compare favorably to their expensive counterparts. They can be used to create integrated separation, collection, and detection ensembles that serve as a basis for eliminating laboratory-confined systems. Beads are tailored to collect and report the presence of specific organisms and diseases. The bead arrays bridge the nano- and micrometer ranges and allow for information to flow efficiently from the micro- to macroscale. The collected digitized data can be analyzed at remote central sites and then used to enable more effective health management as well as aid in the early identification of various global health syndromes. For more information, please read the Full Paper “Location of Biomarkers and Reagents within Agarose Beads of a Programmable Bio-nano-chip” by J. T. McDevitt and co-workers, beginning on page 612.