Carbon Nanotubes: Biocompatibility of Immobilized Aligned Carbon Nanotubes (Small 8/2011) (page 981)
David A. X. Nayagam, Richard A. Williams, Jun Chen, Kylie A. Magee, Jennifer Irwin, Justin Tan, Peter Innis, Ronald T. Leung, Sue Finch, Chris E. Williams, Graeme M. Clark and Gordon G. Wallace
Version of Record online: 14 APR 2011 | DOI: 10.1002/smll.201190025
The cover picture shows a photomicrograph of multiwalled carbon nanotubes (CNTs) implanted within skeletal muscle and viewed under refractive light. The vertically aligned CNTs are immobilized within a biopolymer. After twelve weeks of implantation, the muscle tissue around the implant was harvested and prepared for pathohistological analysis. During tissue processing, the biopolymer was dissolved and there was some artifactual separation of the material from the cavity edge when sectioned for microscopic examination. This procedure was developed to enable evaluation of the tissue reaction to the nanomaterials and the preservation of the surrounding striated muscle, as illustrated in this image. The narrow fibrous tissue band immediately adjacent to the CNTs, and devoid of the cross-striations of the skeletal muscle, indicates a minimal tissue response to the immobilized nanotubes. For more information, please read the Full Paper “Biocompatibility of Immobilized Aligned Carbon Nanotubes” by D. A. X. Nagayam, G. G. Wallace, and co-workers beginning on page 1035.