Cargo-Towing Fuel-Free Magnetic Nanoswimmers for Targeted Drug Delivery (pages 460–467)
Wei Gao, Daniel Kagan, On Shun Pak, Corbin Clawson, Susana Campuzano, Erdembileg Chuluun-Erdene, Erik Shipton, Eric E. Fullerton, Liangfang Zhang, Eric Lauga and Joseph Wang
Article first published online: 15 DEC 2011 | DOI: 10.1002/smll.201101909
Fuel-free nanomotors are essential for future in-vivo biomedical applications. The first example of towing drug-loaded magnetic polymeric particles using magnetically driven fuel free flexible nanomotors is described. The effect of the cargo size upon the swimming performance is evaluated experimentally and compared to a theoretical model. Potential applications of these cargo-towing motors are demonstrated by using the directed delivery of drug-loaded microparticles to HeLa cancer cells in biological media.