Hemocompatibility and Macrophage Response of Pristine and Functionalized Graphene (pages 1251–1263)
Abhilash Sasidharan, Leela S. Panchakarla, Aparna R. Sadanandan, Anusha Ashokan, Parwathy Chandran, Chundayil Madathil Girish, Deepthy Menon, Shantikumar V. Nair, C. N. R. Rao and Manzoor Koyakutty
Article first published online: 15 FEB 2012 | DOI: 10.1002/smll.201102393
Surface functionalization reduces the toxicity of pristine graphene towards macrophage cells in vitro. Macrophages show relatively high intracellular uptake of functionalized, hydrophilic graphene compared to hydrophobic pristine graphene. The excellent compatibility of both types of graphene with human blood components is demonstrated.