TNM, sixth edition: New developments in general concepts and rules

Authors

  • Leslie H. Sobin MD

    Corresponding author
    1. Department of Hepatic and Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC
    • Department of Hepatic and Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306. Fax: (202) 782-9020.
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  • This article is a U.S. Government work and, as such, is in the public domain in the United States of America.

  • The opinions and assertions contained herein are the expressed views of the author and are not to be construed as official or reflecting the views of the departments of the Army or Defense.

Abstract

This article describes changes and clarifications in the 6th edition of TNM that concern site-independent rules, regarding such aspects as sentinel lymph node biopsy, methods to distinguish between micrometastasis and isolated tumor cells, classification of tumors undergoing treatment, tumor deposits in lymph drainage beds, the number of lymph nodes needed for pathologic classification, and classification of residual tumor. These changes mainly reflect advances in diagnosis and treatment, and modulate rather than change the basic rules of classification. Semin. Surg. Oncol. 21:19–22, 2003. Published 2003 Wiley-Liss, Inc.

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