Prophylactic neck dissection in squamous cell carcinoma of oral tongue: A prospective randomized study
Article first published online: 21 AUG 2006
Copyright © 1989 Wiley-Liss, Inc., A Wiley Company
Seminars in Surgical Oncology
Volume 5, Issue 5, pages 327–330, 1989
How to Cite
Fakih, A. R. and Patel, A. R. (1989), Prophylactic neck dissection in squamous cell carcinoma of oral tongue: A prospective randomized study. Semin. Surg. Oncol., 5: 327–330. doi: 10.1002/ssu.2980050507
- Issue published online: 21 AUG 2006
- Article first published online: 21 AUG 2006
- overall disease free survival;
- contralateral neck node metastases;
- carcinoma tongue
This paper presents the first report of an ongoing prospective randomised clinical trial in early T1T2N0 carcinoma of the oral tongue. The problems of regular follow-up in an indigent population from the vast rural expanse of India has been successfully overcome in this trial by close personal follow-up. The trial addresses itself specifically to prophylactic vs. therapeutic surgical management of the neck in T1T2N0 patients with cancer of the oral tongue. Overall disease, free survival (median follow-up 22 months) is higher (64% vs. 47%) in the group receiving prophylactic neck dissection. Disease-free survival for those with positive nodes at prophylactic neck dissection was twice that of those who underwent a subsequent therapeutic neck dissection (57% vs. 28%).
Contralateral neck node metastasis has been identified as a significant factor in neck failures in those patients undergoing simultaneous prophylactic neck dissection.