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Article first published online: 18 JAN 2012
Copyright © 2011 AlphaMed Press
Volume 30, Issue 2, pages 169–179, February 2012
How to Cite
Wang, Y., Yang, D., Song, L., Li, T., Yang, J., Zhang, X. and Le, W. (2012), Mifepristone-Inducible Caspase-1 Expression in Mouse Embryonic Stem Cells Eliminates Tumor Formation but Spares Differentiated Cells In Vitro and In Vivo. STEM CELLS, 30: 169–179. doi: 10.1002/stem.1000
Author contributions: Y.W.: conducting experiments, collection and/or assembly of results, data analysis and interpretation, and manuscript writing; D.Y.: collection and/or assembly of results, data analysis and interpretation, and manuscript writing; L.S., T.L., and J.Y.: collection and/or assembly of data; X.Z.: data analysis and interpretation; W.L.: conception and design, data analysis and interpretation, manuscript writing, financial and administrative support, and final approval of manuscript.
Disclosure of potential conflicts of interest is found at the end of this article.
First published online in STEM CELLSEXPRESS November 30, 2011.
- Issue published online: 18 JAN 2012
- Article first published online: 18 JAN 2012
- Accepted manuscript online: 30 NOV 2011 02:09PM EST
- Manuscript Accepted: 11 NOV 2011
- Manuscript Received: 11 MAY 2011
- Diana Helis Henry Medical Research Foundation
- Baylor College of Medicine
- National Basic Research Program of China. Grant Number: 2007CB947904/2009CB945203/2011CB510003
- Chinese National Nature Science Foundation. Grant Number: 30970925/30730096/81171201
Additional Supporting Information may be found in the online version of this article.
|STEM_1000_sm_suppfigure1.tif||630K||Supporting Figure S1: Caspase-1 mRNA expression determined by RT-PCR in caspase-1-ES cells induced by mifepristone was in a dose-dependent manner (n = 3). * indicated p < .05 and ** indicated p < .01 (compared with mifepristone 0 nM).|
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