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Embryonic Stem Cells/Induced Pluripotent Stem Cells

ZO-1 Regulates Erk, Smad1/5/8, Smad2, and RhoA Activities to Modulate Self-Renewal and Differentiation of Mouse Embryonic Stem Cells†‡§

  1. Jianliang Xu1,
  2. Sophia Beng Hui Lim1,
  3. Mei Yong Ng1,
  4. Safiah Mohamed Ali1,
  5. Jaya P. Kausalya1,
  6. Vachiranee Limviphuvadh2,
  7. Sebastian Maurer-Stroh2,
  8. Walter Hunziker1,¶,*

Article first published online: 20 AUG 2012

DOI: 10.1002/stem.1172

Issue

STEM CELLS

STEM CELLS

Volume 30, Issue 9, pages 1885–1900, September 2012

Additional Information

How to Cite

Xu, J., Lim, S. B. H., Ng, M. Y., Ali, S. M., Kausalya, J. P., Limviphuvadh, V., Maurer-Stroh, S. and Hunziker, W. (2012), ZO-1 Regulates Erk, Smad1/5/8, Smad2, and RhoA Activities to Modulate Self-Renewal and Differentiation of Mouse Embryonic Stem Cells. STEM CELLS, 30: 1885–1900. doi: 10.1002/stem.1172

Author Information

  1. 1

    Epithelial Cell Biology Laboratory, Institute of Molecular and Cell Biology (IMCB), Singapore

  2. 2

    Bioinformatics Institute (BII), Biomolecular Function Discovery Division, Agency for Science Technology and Research (A*STAR), Singapore

  1. Telephone: +65 65869599; Fax: +65 67791117

*Institute of Molecular and Cell Biology, 61 Biopolis Drive, Singapore 138673, Singapore

  1. †

    Author contributions: J.X.: collection and assembly of data, conception and design, manuscript writing, and final approval; S.B.H.L., M.Y.N., S.M.A., and J.P.K.: collection and assembly of data and final approval; V.L. and S.M.S.: data analysis and final approval; W.H.: conception and design, manuscript writing, and final approval.

  2. ‡

    Disclosure of potential conflicts of interest is found at the end of this article.

  3. §

    First published online in STEM CELLSEXPRESS July 10, 2012.

  4. Telephone: +65 65869599; Fax: +65 67791117

Publication History

  1. Issue published online: 20 AUG 2012
  2. Article first published online: 20 AUG 2012
  3. Accepted manuscript online: 10 JUL 2012 04:13PM EST
  4. Manuscript Accepted: 12 JUN 2012
  5. Manuscript Received: 19 SEP 2011

Funded by

  • Agency for Science, Technology and Research (A*STAR), Singapore
  • A*STAR JCO. Grant Number: JCOAG04_FG03_2009

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