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Regenerative Medicine

Transplantation of side population cells restores the function of damaged exocrine glands through clusterin†‡§

  1. Kenji Mishima1,5,
  2. Hiroko Inoue1,
  3. Tatsuaki Nishiyama1,
  4. Yo Mabuchi6,
  5. Yusuke Amano1,
  6. Fumio Ide1,
  7. Makoto Matsui7,
  8. Hiroyuki Yamada8,
  9. Gou Yamamoto5,
  10. Junichi Tanaka5,
  11. Rika Yasuhara5,
  12. Takashi Sakurai9,
  13. Masaichi-Chang-il Lee10,
  14. Kan Chiba11,
  15. Hidetoshi Sumimoto12,
  16. Yutaka Kawakami2,
  17. Yumi Matsuzaki6,
  18. Kazuo Tsubota3,
  19. Ichiro Saito4,¶,*

Article first published online: 20 AUG 2012

DOI: 10.1002/stem.1173

Issue

STEM CELLS

STEM CELLS

Volume 30, Issue 9, pages 1925–1937, September 2012

Additional Information

How to Cite

Mishima, K., Inoue, H., Nishiyama, T., Mabuchi, Y., Amano, Y., Ide, F., Matsui, M., Yamada, H., Yamamoto, G., Tanaka, J., Yasuhara, R., Sakurai, T., Lee, M.-C.-i., Chiba, K., Sumimoto, H., Kawakami, Y., Matsuzaki, Y., Tsubota, K. and Saito, I. (2012), Transplantation of side population cells restores the function of damaged exocrine glands through clusterin. STEM CELLS, 30: 1925–1937. doi: 10.1002/stem.1173

Author Information

  1. 1

    Department of Pathology, Department of Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan

  2. 2

    Division of Cellular Signaling, Institute for Advanced Medical Research, and Keio University School of Medicine, 35-Shinanomachi, Shinjuku-ku, Tokyo, Japan

  3. 3

    Department of Ophthalmology, Keio University School of Medicine, 35-Shinanomachi, Shinjuku-ku, Tokyo, Japan

  4. 4

    Institute for Research and Education of Preemptive Medicine (iREP), Department of Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan

  5. 5

    Department of Oral Pathology, Showa University School of Dentistry, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, Japan

  6. 6

    Department of Physiology,Keio University School of Medicine, 35-Shinanomachi, Shinjuku-ku, Tokyo, Japan

  7. 7

    Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, Kyoto, Japan

  8. 8

    First Department of Oral and Maxillofacial Surgery, and Department of Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan

  9. 9

    Department of Radiology and Division of Pharmacology and ESR Laboratories, Kanagawa Dental College, 82-Inaoka, Yokosuka, Japan

  10. 10

    Department of Clinical Care Medicine, Division of Pharmacology and ESR Laboratories, Kanagawa Dental College, 82-Inaoka, Yokosuka, Japan

  11. 11

    Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan

  12. 12

    Department of Internal Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo, Japan

  1. Telephone: 81-580-8360; Fax: 81-45-572-2888

*Institute for Research and Education of Preemptive Medicine (iREP), Department of Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Japan

  1. †

    Author contributions: K.M. and I.S.: conception and design, Collection and assembly of data, data analysis and interpretation, manuscript writing, and final approval of manuscript; H.I., T.N., Y.M., Y.A., F.I., M.M., H.Y., G.Y., J.T., R.Y., T.S., M.-C.-i.L., K.C., and H.S.: collection and assembly of data and final approval of manuscript; Y.K. and K.T.: data analysis and interpretation and final approval of manuscript; Y.M.: collection and assembly of data, data analysis and interpretation, and final approval of manuscript.

  2. ‡

    Disclosure of potential conflicts of interest is found at the end of this article.

  3. §

    First published online in STEM CELLSEXPRESS July 10, 2012.

  4. Telephone: 81-580-8360; Fax: 81-45-572-2888

Publication History

  1. Issue published online: 20 AUG 2012
  2. Article first published online: 20 AUG 2012
  3. Accepted manuscript online: 10 JUL 2012 04:16PM EST
  4. Manuscript Accepted: 14 JUN 2012
  5. Manuscript Received: 16 NOV 2011

Funded by

  • Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan
  • Grants-in-Aid for Scientific Research
  • Ministry of Health, Labor, and Welfare

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