Cancer Stem Cells

Remodeling of Endogenous Mammary Epithelium by Breast Cancer Stem Cells†‡§

  1. Natesh Parashurama1,¶,
  2. Neethan A. Lobo2,¶,
  3. Ken Ito1,
  4. Adriane R. Mosley2,
  5. Frezghi G. Habte1,
  6. Maider Zabala2,
  7. Bryan R. Smith1,
  8. Jessica Lam2,
  9. Irving L. Weissman2,6,
  10. Michael F. Clarke2,5,8,
  11. Sanjiv S. Gambhir1,3,4,7,‖,*

Article first published online: 20 SEP 2012

DOI: 10.1002/stem.1205

Issue

STEM CELLS

STEM CELLS

Volume 30, Issue 10, pages 2114–2127, October 2012

Additional Information

How to Cite

Parashurama, N., Lobo, N. A., Ito, K., Mosley, A. R., Habte, F. G., Zabala, M., Smith, B. R., Lam, J., Weissman, I. L., Clarke, M. F. and Gambhir, S. S. (2012), Remodeling of Endogenous Mammary Epithelium by Breast Cancer Stem Cells. STEM CELLS, 30: 2114–2127. doi: 10.1002/stem.1205

Author Information

  1. 1

    Molecular Imaging Program @Stanford, Department of Radiology, Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, CA, USA

  2. 2

    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA

  3. 3

    Canary Center for Early Detection of Cancer, Palo Alto, CA, USA

  4. 4

    Departments of BioengineeringStanford University School of Medicine Stanford, CA, USA

  5. 5

    Internal Medicine (Oncology)Stanford University School of Medicine Stanford, CA, USA

  6. 6

    Pathology, Stanford University School of Medicine Stanford, CA, USA

  7. 7

    Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA

  8. 8

    Program in Cellular and Molecular Biology, Stanford University School of Medicine, Stanford, CA, USA

  1. Contributed equally to this work.

  2. ‖

    Telephone: 650-725-2309; Fax: 650-724-4948

*Molecular Imaging Program @Stanford, Department of Radiology, Division of Nuclear Medicine, James H. Clark Center, Stanford University, 318 Campus Drive, E153, Stanford, CA 94305, USA

  1. †

    Author contributions: N.P., N.A.L, M.F.C, and S.S.G.: conceived of, conceptualized, the study. N.P. and N.A.L: designed the experiments. N.P. and N.A.L. performed in vivo experiments with help of J.L., A.R.M., M.Z., and K.I. N.P. and N.A.L. collected and assembled data, with help of K.I. and B.R.S.; N.P, N.L., and F.B.H.: performed data analysis and interpretation; S.S.G. and M.F.C.: provided financial support; N.P., N.A.L, S.S.G, and M.F.C.: wrote and revised the manuscript, with final approval by I.L.W. M.F.C., and S.S.G.

  2. ‡

    Disclosure of potential conflicts of interest is found at the end of this article.

  3. §

    First published online in STEM CELLSEXPRESS August 16, 2012.

  4. Contributed equally to this work.

  5. ‖

    Telephone: 650-725-2309; Fax: 650-724-4948

Publication History

  1. Issue published online: 20 SEP 2012
  2. Article first published online: 20 SEP 2012
  3. Accepted manuscript online: 16 AUG 2012 03:22PM EST
  4. Manuscript Accepted: 3 JUL 2012
  5. Manuscript Received: 30 JAN 2012

Funded by

  • NCI ICMIC. Grant Number: P50CA114747
  • Canary Foundation
  • Stanford Dean's Fellowship
  • Stanford NIBIB T32 Training. Grant Number: EB009035
  • Stanford Neuroscience Microscopy Service (NIS)
  • Two-Photon Microscope

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