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Tissue-Specific Stem Cells
Version of Record online: 19 DEC 2012
Copyright © 2012 AlphaMed Press
Volume 31, Issue 1, pages 146–155, January 2013
How to Cite
Ho, I. A.W., Toh, H. C., Ng, W. H., Teo, Y. L., Guo, C. M., Hui, K. M. and Lam, P. Y.P. (2013), Human Bone Marrow-Derived Mesenchymal Stem Cells Suppress Human Glioma Growth Through Inhibition of Angiogenesis. STEM CELLS, 31: 146–155. doi: 10.1002/stem.1247
Author contributions: I.A.W.H.: conception and design, data analysis and interpretation, and manuscript writing; H.C.T., C.M.G., and W.H.N: provision of study material; Y.L.T.: collection and assembly of data; K.M.H.: administrative support; P.Y.P.L.: conception and design, data analysis and interpretation, manuscript writing, financial support, and final approval of manuscript.
Disclosure of potential conflicts of interest is found at the end of this article.
First published online in STEM CELLSEXPRESS October 3, 2012.
- Issue online: 19 DEC 2012
- Version of Record online: 19 DEC 2012
- Accepted manuscript online: 3 OCT 2012 03:14PM EST
- Manuscript Accepted: 1 AUG 2012
- Manuscript Received: 2 FEB 2012
- SingHealth Foundation and National Medical Research Council, Singapore
Additional Supporting Information may be found in the online version of this article.
|sc-12-0124_sm_SupplTable1.pdf||8K||Table S1. Primer sequences used for qPCR analysis|
|sc-12-0124_sm_SupplFigure1.tif||1587K||Figure. S1 Anti-tumor effect of MSC in glioma/MSC co-culture in vivo Photomicrograph of tumor sections stained for the presence of apoptotic cells using antisingle- stranded DNA in .Gli36, .Gli36/MSC and .Gli36/iNHA tumor. Sections were counterstained with DAPI nuclear stain (blue), green color indicates the anti-singlestranded- DNA-positive cells. Representative images were shown at original magnification x200. Scale bar indicates 50μm.|
|sc-12-0124_sm_SupplFigure2.pdf||253K||Figure. S2 Characterization of EPC EPC were immunostained with antibodies against CD133, CD34, Tie2, VE-cadherin, vegfR-2 and CD45. Mouse IgG1 and rabbit serum were used as negative control for the first five antibodies and CD45, respectively. Cells were counterstained with DAPI nuclear stain (blue); green color showed positively-stained cells. Sections were shown at original magnification x200. Scale bar indicates 100μm.|
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