Additional Supporting Information may be found in the online version of this article.

sc-12-0555_sm_SupplFigure1.tif295KSupplemental Figure 1. Endogenous levels of CYCLIN D1 and CYCLIN E proteins in MFS and MFSiPS cells. Immunoblotting analysis using anti-CNND1 and anti-CNNE antibodies show higher amounts of endogenous CYCLIN D1 and CYCLIN E proteins in MFS and MFSiPS cells compared to their controls. Membranes were stripped and reprobed with β.ACTIN antibody as loading control. Histograms below represent quantification of CYCLIN D1 and CYCLIN E proteins obtained by Image J program.
sc-12-0555_sm_SupplFigure2.tif2963KSupplemental Figure 2. A, Expression profile of BMP ligands and their receptors. qPCR analysis of BMP-2, BMP-4 and BMPRIA and BMPRIB receptors showing similar levels of expression between MFS, MFFiPS cells and their corresponding WT controls. The relative mRNA level in each sample was normalized to its GAPDH content. Values are given as relative to GAPDH expression. B, ELISA assay does not detect significant differences of BMP-2 and -4 ligands between MFS, MFSiPS cells and their WT controls.

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