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Tissue-Specific Stem Cells

Prostaglandin E2 Increases Hematopoietic Stem Cell Survival and Accelerates Hematopoietic Recovery After Radiation Injury†‡§

  1. Rebecca L. Porter1,2,
  2. Mary A. Georger1,2,
  3. Olga Bromberg1,2,
  4. Kathleen E. McGrath3,
  5. Benjamin J. Frisch1,2,
  6. Michael W. Becker1,4,
  7. Laura M. Calvi1,2,¶,*

Article first published online: 12 FEB 2013

DOI: 10.1002/stem.1286

Issue

STEM CELLS

STEM CELLS

Volume 31, Issue 2, pages 372–383, February 2013

Additional Information

How to Cite

Porter, R. L., Georger, M. A., Bromberg, O., McGrath, K. E., Frisch, B. J., Becker, M. W. and Calvi, L. M. (2013), Prostaglandin E2 Increases Hematopoietic Stem Cell Survival and Accelerates Hematopoietic Recovery After Radiation Injury. STEM CELLS, 31: 372–383. doi: 10.1002/stem.1286

Author Information

  1. 1

    Department of Medicine, University of Rochester School of Medicine, Rochester NY

  2. 2

    Endocrine Division, University of Rochester School of Medicine, Rochester NY

  3. 3

    Department of Pediatrics, University of Rochester School of Medicine, Rochester NY

  4. 4

    Hematology Oncology Division, University of Rochester School of Medicine, Rochester NY

  1. Tel.: (585)-275-5011; Fax (585)-273-1288

*Endocrine Division, Department of Medicine, University of Rochester School of Medicine, 601 Elmwood Avenue Box 693, Rochester 14642, New York, USA

  1. †

    Author contributions: R.L.P.: conception and design, collection and assembly of data, data analysis and interpretation, manuscript writing, and final approval of manuscript; M.G: collection and assembly of data and final approval of manuscript; O.B.: collection and assembly of data, data analysis, and final approval of manuscript; K.E.M. and M.W.B.: data analysis and interpretation and final approval of manuscript; B.J.F: collection of data, and final approval of manuscript; L.M.C.: conception and design, financial support, assembly of data, data analysis and interpretation, manuscript writing, and final approval of manuscript.

  2. ‡

    Disclosure of potential conflicts of interest is found at the end of this article.

  3. §

    First published online in STEM CELLSEXPRESS November 21, 2012.

  4. Tel.: (585)-275-5011; Fax (585)-273-1288

Publication History

  1. Issue published online: 12 FEB 2013
  2. Article first published online: 12 FEB 2013
  3. Accepted manuscript online: 21 NOV 2012 12:33AM EST
  4. Manuscript Accepted: 28 OCT 2012
  5. Manuscript Received: 21 JUN 2012

Funded by

  • National Institutes of Health, National Institute of Diabetes, Digestive and Kidney Diseases. Grant Number: R01 DK 076876
  • New York State Stem Cell Initiative
  • NYSTEM Investigator Initiated. Grant Number: #N08G-322
  • Medical Scientist Training Program. Grant Number: NIH T32 GM-07356

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