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sc-12-0494_sm_SupplFigure1.pdf101KSupplemental Figure 1. Augmented protein O-GlcNAcylation may also regulate cell survival by limiting oxidative stress-induced death. Significant oxidative damage to CSCs occurred upon 150 min exposure to 250 μmol/L hydrogen peroxide as assessed by LDH release (*p<0.05 vs 0 μmol/L; n=4/group), whereas increasing O-GlcNAc levels (ThG-mediated OGA inhibition) significantly promoted CSC survival (μp<0.01 vs 250 μmol/L; n=4/group).

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