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REFERENCES

  • 1
    Caro JJ, Salas M, Ward A et al. Anemia as an independent prognostic factor for survival in patients with cancer: A systemic, quantitative review. Cancer 2001; 91: 22142221.
  • 2
    Bennett CL, Silver SM, Djulbegovic B et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA 2008; 299: 914924.
  • 3
    Henke M, Laszig R, Rübe C et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial. Lancet 2003; 362: 12551260.
  • 4
    Leyland-Jones B, Semiglazov V, Pawlicki M et al. Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol 2005; 23: 59605972.
  • 5
    Wright JR, Ung YC, Julian JA et al. Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia. J Clin Oncol 2007; 25: 10271032.
  • 6
    Smith RE Jr., Aapro MS, Ludwig H et al. Darbepoetin alfa for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: Results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol 2008; 26: 10401050.
  • 7
    Oncologic Drugs Advisory Committee meeting briefing materials at http://www.fda.gov/ohrms/dockets/ac/08/briefing/2008–4345b2–01-FDA.pdf. Accessed March 13, 2008.
  • 8
    Blau CA. Erythropoietin in cancer: Presumption of innocence? Stem Cells 2007; 25: 20942097.
  • 9
    Arcasoy MO. Erythropoiesis-stimulating agent use in cancer: Preclinical and clinical perspectives. Clin Cancer Res 2008; 14: 46854690.
  • 10
    Acs G, Acs P, Beckwith SM et al. Erythropoietin and erythropoietin receptor expression in human cancer. Cancer Res 2001; 61: 35613565.
  • 11
    Sinclair AM, Todd MD, Forsythe K et al. Expression and function of erythropoietin receptors in tumors: Implications for the use of erythropoiesis-stimulating agents in cancer patients. Cancer 2007; 110: 477488.
  • 12
    Um M, Gross AW, Lodish HF. A “classical” homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cell Signal 2007; 19: 634645.
  • 13
    Henke M, Mattern D, Pepe M et al. Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol 2006; 24: 47084713.
  • 14
    Elliott S, Busse L, Bass MB et al. Anti-Epo receptor antibodies do not predict Epo receptor expression. Blood 2006; 107: 18921895.
  • 15
    Brines M, Grasso G, Fiordaliso F et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A 2004; 101: 1490714912.
  • 16
    Ihle JN, Gilliland DG. Jak2: normal function and role in hematopoietic disorders. Curr Opin Genet Dev 2007; 17: 814.
  • 17
    Huang LJ, Constantinescu SN, Lodish HF. The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol Cell 2001; 8: 13271338.
  • 18
    Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 2001; 412: 641647.
  • 19
    Morano KA. New tricks for an old dog: The evolving world of Hsp70. Ann N Y Acad Sci 2007; 1113: 114.
  • 20
    Sherman M, Multhoff G. Heat shock proteins in cancer. Ann N Y Acad Sci 2007; 1113: 192201.
  • 21
    Ribeil JA, Zermati Y, Vandekerckhove J et al. HSP70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1. Nature 2007; 445: 102105.
  • 22
    Becker MT, Shores CG, Yu KK et al. Molecular assay to detect metastatic head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2004; 130: 2127.
  • 23
    Prince ME, Sivanandan R, Kaczorowski A et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 2007; 104: 973978.
  • 24
    Phillips TM, Kim K, Vlashi E et al. Effects of recombinant erythropoietin on breast cancer-initiating cells. Neoplasia 2007; 9: 11221129.
  • 25
    Palacios R, Steinmetz M. Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 1985; 41: 727734.
  • 26
    Inoue Y, Tsushima H, Ando K et al. Chemokine expression in human erythroid leukemia cell line AS-E2: Macrophage inflammatory protein-3alpha/CCL20 is induced by inflammatory cytokines. Exp Hematol 2006; 34: 1926.
  • 27
    Vandesompele J, De Preter K, Pattyn F et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: RESEARCH0034.
  • 28
    Paul I, Lappin TR, Maxwell P et al. Pre-operative plasma erythropoietin concentration and survival following surgery for non-small cell lung cancer. Lung Cancer 2006; 51: 329334.
  • 29
    Fu P, Jiang X, Arcasoy MO. Constitutively active erythropoietin receptor expression in breast cancer cells promotes cellular proliferation and migration through a MAP-kinase dependent pathway. Biochem Biophys Res Commun 2009; 379: 696701.
  • 30
    Antonov J, Goldstein DR, Oberli A et al. Reliable gene expression measurements from degraded RNA by quantitative real-time PCR depend on short amplicons and a proper normalization. Lab Invest 2005; 85: 10401050.
  • 31
    Grizzi F, Colombo P, Taverna G et al. Geometry of human vascular system: is it an obstacle for quantifying antiangiogenic therapies? Appl Immunohistochem Mol Morphol 2007; 15: 134139.
  • 32
    Cronin M, Pho M, Dutta D et al. Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay. Am J Pathol 2004; 164: 3542.
  • 33
    Sinclair AM, Rogers N, Busse L et al. Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells. Br J Cancer 2008; 98: 10591067.
  • 34
    Vallet JL, Freking BA, Leymaster KA et al. Allelic variation in the erythropoietin receptor gene is associated with uterine capacity and litter size in swine. Anim Genet 2005; 36: 97103.
  • 35
    Wang R, Lagakos SW, Ware JH et al. Statistics in medicine–reporting of subgroup analyses in clinical trials. N Engl J Med 2007; 357: 21892194.