Embryonic Stem Cells/Induced Pluripotent Stem Cells
Version of Record online: 19 JUN 2009
Copyright © 2009 AlphaMed Press
Volume 27, Issue 9, pages 2136–2145, September 2009
How to Cite
Chen, Z., Liu, Z., Huang, J., Amano, T., Li, C., Cao, S., Wu, C., Liu, B., Zhou, L., Carter, M. G., Keefe, D. L., Yang, X. and Liu, L. (2009), Birth of Parthenote Mice Directly from Parthenogenetic Embryonic Stem Cells. STEM CELLS, 27: 2136–2145. doi: 10.1002/stem.158
Author contributions: L.L.: conception and design, financial support, final approval of manuscript; Z.C.: collection and assembly of data, data analysis and interpretation, manuscript writing; J.H.: collection and assembly of data, data analysis and interpretation; Z.L., C.L., B.L., C.W., S.C., T.A.: collection and assembly of data; L.Z.: provision of study material; M.G.C.: collection and assembly of data, data analysis and interpretation; D.L.K., X.Y., data analysis and interpretation, financial support, final approval of manuscript.
First published online in STEM CELLS EXPRESS June 19, 2009.
- Issue online: 8 SEP 2009
- Version of Record online: 19 JUN 2009
- Accepted manuscript online: 19 JUN 2009 12:00AM EST
- Manuscript Accepted: 9 JUN 2009
- Manuscript Received: 22 MAR 2009
- National Natural Science Foundation, Science and Technology Division of Guangdong Province, and China Ministry of Science and Technology. Grant Number: 2009CB941000
- USDA-ARS. Grant Numbers: AG 58-1265-2-018, 58-1265-2-020
- 1Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature 1984; 308: 548–550., , .
- 2Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 1984; 37: 179–183., .
- 3Abnormal development of embryonic and extraembryonic cell lineages in parthenogenetic mouse embryos. Dev Dyn 1994; 201: 11–28., , .
- 4The non-viability of uniparental mouse conceptuses correlates with the loss of the products of imprinted genes. Mech Dev 1994; 46: 55–62., , et al.
- 5Regulated expression of two sets of paternally imprinted genes is necessary for mouse parthenogenetic development to term. Reproduction 2006; 131: 481–488., , et al.
- 6A functional analysis of imprinting in parthenogenetic embryonic stem cells. Development 1994; 120: 1473–1482., , et al.
- 7Stem cell defects in parthenogenetic peri-implantation embryos. Development 1995; 121: 2069–2077., .
- 8Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines. Development 1994; 120: 1651–1660., .
- 9Dynamics of the calcium signal that triggers mammalian egg activation. Int Rev Cytol 1994; 152: 183–222., .
- 10Egg activation is the result of calcium signal summation in the mouse. Reproduction 2006; 131: 27–34., , et al.
- 11Calcium-independent, meiotic spindle-dependent metaphase-to-interphase transition in phorbol ester-treated mouse eggs. Dev Biol 1995; 171: 111–122., .
- 12Calcium oscillations and protein synthesis inhibition synergistically activate mouse oocytes. Mol Reprod Dev 1995; 41: 84–90., , .
- 13Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998; 394: 369–374., , et al.
- 14Production of offspring from one-day-old oocytes stored at room temperature. J Reprod Dev 2004; 50: 627–637., , et al.
- 15In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007; 448: 318–324., , et al.
- 16Parthenogenetic stem cells in nonhuman primates. Science 2002; 295: 819., , et al.
- 17Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci U S A 2003; 100( suppl 1): 11911–11916., , et al.
- 18Histocompatible embryonic stem cells by parthenogenesis. Science 2007; 315: 482–486., , et al.
- 19Haploidy but not parthenogenetic activation leads to increased incidence of apoptosis in mouse embryos. Biol Reprod 2002; 66: 204–210., , .
- 20Effect of ploidy and parental genome composition on expression of Oct-4 protein in mouse embryos. Gene Expr Patterns 2004; 4: 433–441., , .
- 21Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113: 643–655., , et al.
- 22Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell 2007; 1: 346–352., , et al.
- 23Multilineage potential of homozygous stem cells derived from metaphase II oocytes. Stem Cells 2003; 21: 152–161., , et al.
- 24Systematic non-uniform distribution of parthenogenetic cells in adult mouse chimaeras. Development 1989; 106: 321–324., , .
- 25Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci U S A 1993; 90: 8424–8428., , et al.
- 26Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc Natl Acad Sci U S A 2001; 98: 6209–6214., , et al.
- 27Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat Biotechnol 2002; 20: 455–459., , et al.
- 28Embryonic stem cells alone are able to support fetal development in the mouse. Development 1990; 110: 815–821., , et al.
- 29Defective chorioallantoic fusion in mid-gestation lethality of parthenogenone<–>tetraploid chimeras. Dev Biol 1996; 173: 447–458., , et al.
- 30Birth of parthenogenetic mice that can develop to adulthood. Nature 2004; 428: 860–864., , et al.
- 31Prenatal fate of parthenogenetic cells in mouse aggregation chimaeras. Development 1987; 101: 67–71., , et al.
- 32Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells. Hum Mol Genet 2009; 18: 2177–2187., , et al.
- 33Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes. Development 1998; 125: 2273–2282., , et al.
- 34Epigenetic instability in ES cells and cloned mice. Science 2001; 293: 95–97., , et al.
- 35The genetic heterozygosity and fitness of tetraploid embryos and embryonic stem cells are crucial parameters influencing survival of mice derived from embryonic stem cells by tetraploid embryo aggregation. Reproduction 2005; 130: 53–59., , et al.
- 36Passage number affects the pluripotency of mouse embryonic stem cells as judged by tetraploid embryo aggregation. Cell Tissue Res 2007; 327: 607–614., , et al.
- 37Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation. Methods Enzymol 2003; 365: 25–39., .
- 38Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev 1995; 9: 3097–3108., .
- 39Dynamics of global gene expression changes during mouse preimplantation development. Dev Cell 2004; 6: 117–131., , et al.
- 40Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 2002; 12: 432–438., , .
- 41Genesis of embryonic stem cells. Philos Trans R Soc Lond B Biol Sci 2003; 358: 1397–1402., .
- 42The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631–642., , et al.
- 43The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol 2006; 26: 7539–7549., , et al.