Additional supporting information available online.

STEM_169_sm_SuppFig1.tif1274KSupplemental data 1. Cardiac morphology after myocardial infarction Supplemental data 1A shows the kinetic of the protocol. Supplemental data 1B shows cardiac morphology (Hematoxylin/Eosin staining, panels a and c) and tissue fibrosis (Red Sirius staining, panels b and d) of the left ventricle 15 days after permanent ligation of the interventricular artery as compared to sham-operated rats (magnification x 200) (n≥5 animals per group).
STEM_169_sm_SuppFig2.tif1759KSupplemental data 2. MSCs survival and cardiac angiogenesis after graft. Supplemental data 2A shows QD-labeled cells (panel a), the number of apoptotic (panel b) or proliferative MSCs (panel c). Supplemental data 2B shows quantification of angiogenesis in the scar area of rats injected with untreated or melatonin-treated MSCs (n≥5 animals per group).

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