SEARCH

SEARCH BY CITATION

References

  • 1
    Rohde LA, Heisenberg CP. Zebrafish gastrulation: cell movements, signals, and mechanisms. Int Rev Cytol 2007; 261: 159192.
  • 2
    Tam PP, Loebel DA. Gene function in mouse embryogenesis: get set for gastrulation. Nat Rev Genet 2007; 8: 368381.
  • 3
    Tam PP, Loebel DA, Tanaka SS. Building the mouse gastrula: signals, asymmetry and lineages. Curr Opin Genet Dev 2006; 16: 419425.
  • 4
    Ecochard V, Cayrol C, Rey S et al. A novel Xenopus mix-like gene milk involved in the control of the endomesodermal fates. Development 1998; 125: 25772585.
  • 5
    Guo W, Chan AP, Liang H et al. A human Mix-like homeobox gene MIXL shows functional similarity to Xenopus Mix. 1. Blood 2002; 100: 8995.
  • 6
    Henry GL, Melton DA. Mixer, a homeobox gene required for endoderm development. Science 1998; 281: 9196.
  • 7
    Vize PD. DNA sequences mediating the transcriptional response of the Mix. 2 homeobox gene to mesoderm induction. Dev Biol 1996; 177: 226231.
  • 8
    Tada M, Casey ES, Fairclough L et al. Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm. Development 1998; 125: 39974006.
  • 9
    Stein S, Roeser T, Kessel M. CMIX, a paired-type homeobox gene expressed before and during formation of the avian primitive streak. Mech Dev 1998; 75: 163165.
  • 10
    Sahr K, Dias DC, Sanchez R et al. Structure, upstream promoter region, and functional domains of a mouse and human Mix paired-like homeobox gene. Gene 2002; 291: 135147.
  • 11
    Rosa FM. Mix. 1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 1989; 57: 965974.
  • 12
    Robb L, Hartley L, Begley CG et al. Cloning, expression analysis, and chromosomal localization of murine and human homologues of a Xenopus mix gene. Dev Dyn 2000; 219: 497504.
  • 13
    Poulain M, Lepage T. Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates endoderm specification in zebrafish. Development 2002; 129: 49014914.
  • 14
    Pearce JJ, Evans MJ. Mml, a mouse Mix-like gene expressed in the primitive streak. Mech Dev 1999; 87: 189192.
  • 15
    Peale FV Jr, Sugden L, Bothwell M. Characterization of CMIX, a chicken homeobox gene related to the Xenopus gene mix.1. Mech Dev 1998; 75: 167170.
  • 16
    Mead PE, Brivanlou IH, Kelley CM et al. BMP-4-responsive regulation of dorsal-ventral patterning by the homeobox protein Mix. 1. Nature 1996; 382: 357360.
  • 17
    Mead PE, Zhou Y, Lustig KD et al. Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. Proc Natl Acad Sci U S A 1998; 95: 1125111256.
  • 18
    Kikuchi Y, Trinh LA, Reiter JF et al. The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. Genes Dev 2000; 14: 12791289.
  • 19
    Trinh LA, Meyer D, Stainier DY. The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish. Development 2003; 130: 49894998.
  • 20
    Pick M, Azzola L, Mossman A et al. Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. Stem Cells 2007; 25: 22062214.
  • 21
    Ng ES, Azzola L, Sourris K et al. The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development 2005; 132: 873884.
  • 22
    Lemaire P, Darras S, Caillol D et al. A role for the vegetally expressed Xenopus gene Mix. 1 in endoderm formation and in the restriction of mesoderm to the marginal zone. Development 1998; 125: 23712380.
  • 23
    Kunwar PS, Zimmerman S, Bennett JT et al. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development 2003; 130: 55895599.
  • 24
    Hart AH, Willson TA, Wong M et al. Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1. Biochem Biophys Res Commun 2005; 333: 13611369.
  • 25
    Mohn D, Chen SW, Dias DC et al. Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos. Dev Dyn 2003; 226: 446459.
  • 26
    Hart AH, Hartley L, Sourris K et al. Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development 2002; 129: 35973608.
  • 27
    Izumi N, Era T, Akimaru H et al. Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference. Stem Cells 2007; 25: 16641674.
  • 28
    Willey S, Ayuso-Sacido A, Zhang H et al. Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood 2006; 107: 31223130.
  • 29
    Latinkic BV, Smith JC. Goosecoid and mix.1 repress Brachyury expression and are required for head formation in Xenopus. Development 1999; 126: 17691779.
  • 30
    Germain S, Howell M, Esslemont GM et al. Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif. Genes Dev 2000; 14: 435451.
  • 31
    Blum M, Gaunt SJ, Cho KW et al. Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 1992; 69: 10971106.
  • 32
    Faust C, Schumacher A, Holdener B et al. The eed mutation disrupts anterior mesoderm production in mice. Development 1995; 121: 273285.
  • 33
    Perea-Gómez A, Shawlot W, Sasaki H et al. HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development 1999; 126: 44994511.
  • 34
    Norris DP, Brennan J, Bikoff EK et al. The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development 2002; 129: 34553468.
  • 35
    Yeung KC, Inostroza JA, Mermelstein FH et al. Structure-function analysis of the TBP-binding protein Dr1 reveals a mechanism for repression of class II gene transcription. Genes Dev 1994; 8: 20972109.
  • 36
    Kennedy M, Keller GM. Hematopoietic commitment of ES cells in culture. Methods Enzymol 2003; 365: 3959.
  • 37
    Pollock RM. Determination of protein-DNA sequence specificity by PCR-assisted binding-site selection. Curr Protoc Mol Biol 2001;Chapter 12:Unit 12.11.
  • 38
    Wilson D, Sheng G, Lecuit T et al. Cooperative dimerization of paired class homeo domains on DNA. Genes Dev 1993; 7: 21202134.
  • 39
    Crooks GE, Hon G, Chandonia JM et al. WebLogo: a sequence logo generator. Genome Res 2004; 14: 11881190.
  • 40
    Catron KM, Iler N, Abate C. Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins. Mol Cell Biol 1993; 13: 23542365.
  • 41
    Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Vol 3. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
  • 42
    Aparicio O, Geisberg JV, Sekinger E et al. Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Curr Protoc Mol Biol 2005; Chapter 21:Unit 21.23.
  • 43
    Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 2005; 19: 11291155.
  • 44
    Tada S, Era T, Furusawa C et al. Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 2005; 132: 43634374.
  • 45
    Takebe A, Era T, Okada M et al. Microarray analysis of PDGFR alpha+ populations in ES cell differentiation culture identifies genes involved in differentiation of mesoderm and mesenchyme including ARID3b that is essential for development of embryonic mesenchymal cells. Dev Biol 2006; 293: 2537.
  • 46
    Mikkola HK, Fujiwara Y, Schlaeger TM et al. Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 2003; 101: 508516.
  • 47
    Watabe T, Kim S, Candia A et al. Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev 1995; 9: 30383050.
  • 48
    Wilson DS, Sheng G, Jun S et al. Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis. Proc Natl Acad Sci U S A 1996; 93: 68866891.
  • 49
    Mailhos C, Andre S, Mollereau B et al. Drosophila Goosecoid requires a conserved heptapeptide for repression of paired-class homeoprotein activators. Development 1998; 125: 937947.
  • 50
    Qu S, Tucker SC, Zhao Q et al. Physical and genetic interactions between Alx4 and Cart1. Development 1999; 126: 359369.
  • 51
    Tucker SC, Wisdom R. Site-specific heterodimerization by paired class homeodomain proteins mediates selective transcriptional responses. J Biol Chem 1999; 274: 3232532332.
  • 52
    Blumberg B, Wright CV, De Robertis EM et al. Organizer-specific homeobox genes in Xenopus laevis embryos. Science 1991; 253: 194196.
  • 53
    Cho KW, Blumberg B, Steinbeisser H et al. Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 1991; 67: 11111120.
  • 54
    Yamada G, Mansouri A, Torres M et al. Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development 1995; 121: 29172922.
  • 55
    Rivera-Pérez JA, Mallo M, Gendron-Maguire M et al. Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development. Development 1995; 121: 30053012.
  • 56
    De Robertis EM. Goosecoid and gastrulation. In: SternCD, ed. Gastrulation: From Cells to Embryos. 1st ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2004: 581589.
  • 57
    Izzi L, Silvestri C, von Both I et al. Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J 2007; 26: 31323143.