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Embryonic Stem Cells/Induced Pluripotent Stem Cells
Version of Record online: 26 OCT 2010
Copyright © 2010 AlphaMed Press
Volume 28, Issue 10, pages 1772–1781, October 2010
How to Cite
Sterneckert, J., Stehling, M., Bernemann, C., Araúzo-Bravo, M. J., Greber, B., Gentile, L., Ortmeier, C., Sinn, M., Wu, G., Ruau, D., Zenke, M., Brintrup, R., Klein, D. C., Ko, K. and Schöler, H. R. (2010), Neural Induction Intermediates Exhibit Distinct Roles of Fgf Signaling. STEM CELLS, 28: 1772–1781. doi: 10.1002/stem.498
J.S.: conception and design, collection and/or assembly of data, data analysis and interpretation, manuscript writing; M.S.: collection and/or assembly of data; C.B.: provision of study material or patients; M.J.A.-B.: data analysis and interpretation; B.G.: collection and/or assembly of data; L.G.: collection and/or assembly of data; C.O.: collection and/or assembly of data; M.S.: collection and/or assembly of data; G.W.: collection and/or assembly of data; D.R.: collection and/or assembly of data; M.Z.: collection and/or assembly of data; R.B.: collection and/or assembly of data; D.C.K.: collection and/or assembly of data; K.K.: provision of study material or patients; H.R.S.: conception and design, financial support, final approval of manuscript.
Disclosure of potential conflicts of interest is found at the end of this article.
First published online in STEM CELLS EXPRESS August 16, 2010.
- Issue online: 26 OCT 2010
- Version of Record online: 26 OCT 2010
- Accepted manuscript online: 16 AUG 2010 12:00AM EST
- Manuscript Accepted: 5 AUG 2010
- Manuscript Received: 26 MAR 2010
Additional Supporting Information may be found in the online version of this article.
|STEM_498_sm_SuppFig1.tif||22791K||Supporting Information Figure 1. Differentiation of ES cells into neuronal lineage. Neurons (TuJ1-positive) formed from ES cells after 9 days in N2B27 medium.|
|STEM_498_sm_SuppFig2.tif||325K||Supporting Information Figure 2. Relative E-cadherin expression. E-cadherin expression levels in ES cells and their derivatives.|
|STEM_498_sm_SuppFig3.tif||319K||Supporting Information Figure 3. Relative competence for Brachyury induction by BMP. Relative expression levels of Brachyury in the presence or absence of BMP stimulation for 4 hours for the indicated cell types.|
|STEM_498_sm_SuppFig4.tif||19382K||Supporting Information Figure 4. Chimera formation potential of ES cell–derived EpiSCs. Blastocysts formed from ES cells or ES cell–derived EpiSCs aggregated with morulas.|
|STEM_498_sm_SuppFig5.tif||2444K||Supporting Information Figure 5. Microarray comparison of EpiSCs derived from embryonic epiblast or EpiInt cells. Scatter plot depicting the expression profile of epiblast stem cells derived from embryonic epiblast (EPId) versus that of differentiated ES cell–derived (ESd). Number of similar expressed genes: 44,873 (99.5℅); Correlation coefficient R; 0.985; Number of different expressed genes: 228 (0.506℅) (using a 2 fold change threshold in log2 scale).|
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