• 1
    Civin CI, Trischman T, Fackler MJ, Bernstein I, Buhring H, Campos L, Greaves MF, Kamoun M, Katz D, Lansdorp P, Look T, Seed B, Sutherland DR, Tindle R, Uchanska-Zeigler B. Summary of CD34 cluster workshop section. In: Leucocyte Typing IV W.Knapp et al., eds. Oxford Univ Press 1989; 818825.
  • 2
    Andrews RG, Singer JW, Bernstein ID. Human hematopoietic precursors in long-term culture: single CD34+ cells that lack detectable T cell, B cell, and myeloid cell antigens produce multiple colony-forming cells when cultured with marrow stromal cells. J Exp Med 1990; 172: 355358.
  • 3
    Berenson RJ, Andrews RG, Bensinger WI, Kalamasz D, Knitter G, Buckner CD, Bernstein ID. Antigen CD34-positive marrow cells engraft lethally irradiated baboons. J Clin Invest 1988; 81: 951955.
  • 4
    Wagermaker G, van Gils FCJM, Bart-Baumeister JAK, Weilenger JJ, Levinsky RJ. Sustained engraftment of allogeneic CD34 positive hemopoietic stem cells in rhesus monkeys. Exp Hematol 1990; 18: 704a.
  • 5
    Berenson RJ, Bensinger WI, Hill RS, Andrews RG, Garcia-Lopez J, Kalamaz DF, Still BJ, Spitzer G, Buckner D, Bernstein ID, Thomas ED. Engraftment after infusion of CD34+ Marrow Cells in patients with breast cancer or neuroblastoma. Blood 1991; 77: 17171722.
  • 6
    Fina L, Molgaard HV, Robertson D, Bradley NJ, Monaghan P, Delia D, Sutherland DR, Baker MA, Greaves MF. Expression of the CD34 gene in vascular ECs. Blood 1990; 75: 24172426.
  • 7
    Greaves MF, Brown J, Molgaard HV, Robertson D, Delia D, Sutherland DR. Molecular features of CD34: a hemopoietic progenitor cell-associated molecule. Leukemia 1992; 6 (Suppl 1): 3136.
  • 8
    Sutherland DR, Keating A. The CD34 antigen: Structure, biology and potential clinical applications. J Hematotherapy 1992; 1: 115129.
  • 9
    Watt SM, Karhi K, Garter K, Furley AJW, Katz FE, Healy LE, Altass U, Bradley NJ, Sutherland DR, Levinsky R, Greaves MF. Distribution and epitope analysis of the cell membrane glycoprotein (HPCA-1) associated with human hemopoietic progenitor cells. Leukemia 1987; 1: 417426.
  • 10
    Otulakowski GL, Shewen PE, Udoh AE, Mellors A, Wilkie BN. Proteolysis of sialoglycoprotein by Pasteurella haemolytica cytotoxic culture supernatant. Infect Immun 1991; 42: 6470.
  • 11
    Sutherland DR, Abdullah KM, Cyopick P, Mellors A. Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44 and CD45 by a novel glycoprotease from Pasteurella haemolytica. J Immunol 1992; 148: 14581464.
  • 12
    Sutherland DR, Marsh JCW, Davidson J, Baker MA, Keating A, Mellors A. Differential sensitivity of CD34 epitopes to cleavage by Pasteurella haemolytica glycoprotease: implications for purification of CD34-positive progenitor cells. Exp Hematol 1992; 20: 590599.
  • 13
    Lansdorp PM, Sutherland HJ, Eaves CJ. Selective expression of CD45 isoforms on functional subpopulations of CD34+ hemopoietic cells from human bone marrow. J Exp Med 1990; 172: 363366.
  • 14
    Sutherland DR, Watt SM, Dowden G, Karhi K, Baker MA, Greaves MF, Smart JS. Structural and partial amino acid sequence analysis of the human hemopoietic progenitor cell antigen CD34. Leukemia 1988; 2: 793803.
  • 15
    Fackler MJ, Civin CI, Sutherland DR, Baker MA, May WS. Activated Protein Kinase C directly phosphorylates the CD34 antigen on hematopoietic cells. J Biol Chem 1990; 265: 1105611061.
  • 16
    Sutherland DR, Fackler MJ, May WS, Matthews K, Baker MA. Activated protein kinase C directly phosphorylates the CD34 antigen in fresh acute lymphoblastic leukemia cells. Leukemia and Lymphoma 1992; 8: 337344.
  • 17
    Fackler MJ, Civin CI, May WS. Up-regulation of surface CD34 is associated with Protein Kinase C-mediated hyperphosphorylation of CD34. J Biol Chem 1992; 267; 1754017546.
  • 18
    Simmons DL, Satterthwaite AB, Tenen DG, Seed B. Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 1992; 148: 267271.
  • 19
    Molgaard HV, Spurr NK, Greaves MF. The hemopoietic stem cell antigen CD34 is encoded by a gene located on chromosome 1. Leukemia 1989; 3: 773776.
  • 20
    Howell SM, Molgaard HV, Greaves MF, Spurr NK. Localization of the gene coding for the hemopoietic stem cell antigen CD34 to chromosome Iq32. Human Genet 1991; 87: 625627.
  • 21
    Brown J, Greaves MF, Molgaard HV. The gene encoding the stem cell antigen CD34 is conserved in mouse and expressed in hemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int Immunol 1991; 3: 175184.
  • 22
    O'Reilly RJ. Allogeneic bone marrow transplantation: current status and future directions. Blood 1983; 62: 942964.
  • 23
    Kessinger A, Armitage JO. The evolving role of autologous peripheral stem cell transplantation following high-dose therapy for malignancies. Blood 1991; 77: 211213.
  • 24
    Wagner JE, Broxmeyer HE, Byrd RL, Zehnbauer B, Schmeckpeper B, Shah N, Griffin C, Emanuel PD, Zuckerman S, Cooper S, Carow C, Bias W, Santos GW. Transplantation of umbilical cord blood after myeloablative therapy: Analysis of engraftment. Blood 1992; 79: 18741881.
  • 25
    Collins RH, Anastasi J, Terstappen LWMM, Nikaein A, Feng J, Fay JW, Klintmalm G, Stone M. Donor-derived long-term multilineage hematopoiesis in a liver-transplant recipient. NEJM 1993; 328: 762765.
  • 26
    Treleaven JG, Mehta J. Bone marrow and peripheral blood stem cell harvesting. J Hematotherapy 1992; 1: 215223.
  • 27
    Wunder E, Sovolat H, Fritsch G, Silvestri F, Henon P, Serke S. Report on the European workshop on peripheral blood stem cell determination and standardization. Mulhouse, France, February 6–8 and 14–15, 1992. J Hematotherapy 1992; 1: 131142.
  • 28
    Siena S, Bregni M, Belli N, Ravagnani F, Gandola L, Stern AC, Lansdorp PM, Bonadona G, Massimo G. Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Blood 1991; 77: 400409.
  • 29
    Civin CI, Strauss LC, Fackler MJ, Trischmann TM, Wiley JM. Positive stem cell selection—basic science. In: GrossS, GeeAP, Worthington-WhiteD, eds. Progress in Clinical and Biological Research: Bone Marrow Purging and Processing, Alan R. Liss, Inc. 1990; 333: 387402.
  • 30
    Marsh JCW, Sutherland DR, Davidson J, Mellors A, Keating A. Retention of progenitor cell function in CD34+ cells purified using a novel O-sialo-glycoprotease. Leukemia 1992; 6: 926934.
  • 31
    Huang S, Terstappen LWMM. Formation of hematopoietic microenvironment and hematopoietic stem cells from single human bone marrow stem cells. Nature 1992; 360: 745749.
  • 32
    Srour E, Brandt JE, Briddell RA, Grigsby S, Leemius T, Hoffman R. Long-term generation and expansion of human primitive hematopoietic progenitor cells in vitro. Blood 1993; 81: 661669.
  • 33
    Baum CM, Weissman IL, Tsukamoto A, Buckle A-M, Peault B. Isolation of a candidate human hematopoietic stem cell population. Proc Nat Acad Sci USA 1992; 89: 28042808.
  • 34
    Coulombel L, Kalousek D, Eaves CJ, Gupta CM, Eaves AC. Long-term marrow culture reveals chromosomally normal hematopoietic progenitor cells in patients with Ph1 chromosome positive chronic myeloid leukemia. N Engl J Med 1983; 308: 14931498.
  • 35
    Barnett MJ, Eaves CJ, Philips G, Kalousek DK, Klingemann HG, Lansdorp PM, Reece DE, Shephard JD, Shaw GJ, Eaves AC. Successful autografting in chronic myeloid leukemia after maintenance of marrow in culture. Bone Marrow Transplant 1989; 4: 345351.
  • 36
    Konopka JB, Watanabe SM, Witte ON. An alteration of the human c- abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 1984; 37: 10351042.
  • 37
    Verfaille CM, Miller WJ, Boylan K, McGlave PB. Selection of benign primitive hematopoietic progenitors in chronic myelogenous leukemia on the basis of HLA-DR antigen expression. Blood 1992; 79: 10031010.