SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Chopp M, Zhang XH, Li Y et al. Spinal cord injury in rat: Treatment with bone marrow stromal cell transplantation. Neuroreport 2000; 11: 30013005.
  • 2
    Shen LH, Li Y, Chen J et al. Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke. J Cereb Blood Flow Metab 2007; 27: 613.
  • 3
    Lee JK, Jin HK, Bae JS. Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model. Neurosci Lett 2009; 450: 136141.
  • 4
    Lee JK, Jin HK, Endo S et al. Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease mice by modulation of immune responses. Stem Cells 2010; 28: 329343.
  • 5
    Malm TM, Koistinaho M, Parepalo M et al. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice. Neurobiol Dis 2005; 18: 134142.
  • 6
    Stalder AK, Ermini F, Bondolfi L et al. Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice. J Neurosci 2005; 25: 1112511132.
  • 7
    Simard AR, Soulet D, Gowing G et al. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 2006; 49: 489502.
  • 8
    Simard AR, Rivest S. Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease. Mol Psychiatry 2006; 11: 327335.
  • 9
    Tsai KJ, Tsai YC, Shen CK. G-CSF rescues the memory impairment of animal models of Alzheimer's disease. J Exp Med 2007; 204: 12731280.
  • 10
    Boissonneault V, Filali M, Lessard M et al. Powerful beneficial effects of macrophage colony-stimulating factor on beta-amyloid deposition and cognitive impairment in Alzheimer's disease. Brain 2009; 132: 10781092.
  • 11
    Sanchez-Ramos J, Song S, Sava V et al. Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice. Neuroscience 2009; 163: 5572.
  • 12
    Cashen AF, Link D, Devine S et al. Cytokines and stem cell mobilization for autologous and allogeneic transplantation. Curr Hematol Rep 2004; 3: 406412.
  • 13
    Kawada H, Takizawa S, Takanashi T et al. Administration of hematopoietic cytokines in the subacute phase after cerebral infarction is effective for functional recovery facilitating proliferation of intrinsic neural stem/progenitor cells and transition of bone marrow-derived neuronal cells. Circulation 2006; 113: 701710.
  • 14
    Koda M, Nishio Y, Kamada T et al. Granulocyte colony-stimulating factor (G-CSF) mobilizes bone marrow-derived cells into injured spinal cord and promotes functional recovery after compression-induced spinal cord injury in mice. Brain Res 2007; 1149: 223231.
  • 15
    Broxmeyer HE, Orschell CM, Clapp DW et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med 2005; 201: 13071318.
  • 16
    De Clercq E. The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil). Biochem Pharmacol 2009; 77: 16551664.
  • 17
    Pitchford SC, Furze RC, Jones CP et al. Differential mobilization of subsets of progenitor cells from the bone marrow. Cell Stem Cell 2009; 4: 6272.
  • 18
    Aiuti A, Webb IJ, Bleul C et al. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 1997; 185: 111120.
  • 19
    Stellos K, Gawaz M. Platelets and stromal cell-derived factor-1 in progenitor cell recruitment. Semin Thromb Hemost 2007; 33: 159164.
  • 20
    Shyu WC, Lin SZ, Yen PS et al. Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats. J Pharmacol Exp Ther 2008; 324: 834849.
  • 21
    Hsiao K, Chapman P, Nilsen S et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996; 274: 99102.
  • 22
    Duff K, Eckman C, Zehr C et al. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1. Nature 1996; 383: 710713.
  • 23
    Friedenstein AJ, Deriglasova UF, Kulagina NN et al. Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method. Exp Hematol 1974; 2: 8392.
  • 24
    Hickman SE, Allison EK, El Khoury J. Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice. J Neurosci 2008; 28: 83548360.
  • 25
    Furuya T, Tanaka R, Urabe T et al. Establishment of modified chimeric mice using GFP bone marrow as a model for neurological disorders. Neuroreport 2003; 14: 629631.
  • 26
    Zavala F, Abad S, Ezine S et al. G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine- and cytokine-based immune deviation. J Immunol 2002; 168: 20112019.
  • 27
    Janelsins MC, Mastrangelo MA, Oddo S et al. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. J Neuroinflammation 2005; 2: 23.
  • 28
    Nichol KE, Poon WW, Parachikova AI et al. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid. J Neuroinflammation 2008; 5: 13.
  • 29
    Lyons A, Griffin RJ, Costelloe CE et al. IL-4 attenuates the neuroinflammation induced by amyloid-beta in vivo and in vitro. J Neurochem 2007; 101: 771781.
  • 30
    Butovsky O, Talpalar AE, Ben-Yaakov K et al. Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Mol Cell Neurosci 2005; 29: 381393.
  • 31
    Butovsky O, Ziv Y, Schwartz A et al. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci 2006; 31: 149160.
  • 32
    Colton CA. Heterogeneity of microglial activation in the innate immune response in the brain. J Neuroimmune Pharmacol 2009; 4: 399418.
  • 33
    Tran PB, Ren D, Veldhouse TJ et al. Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells. J Neurosci Res 2004; 76: 2034.
  • 34
    Schneider A, Kruger C, Steigleder T et al. The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest 2005; 115: 20832098.
  • 35
    Kolodziej A, Schulz S, Guyon A et al. Tonic activation of CXC chemokine receptor 4 in immature granule cells supports neurogenesis in the adult dentate gyrus. J Neurosci 2008; 28: 44884500.
  • 36
    Laske C, Stellos K, Eschweiler GW et al. Decreased CXCL12 (SDF-1) plasma levels in early Alzheimer's disease: A contribution to a deficient hematopoietic brain support? J Alzheimers Dis 2008; 15: 8395.
  • 37
    Laske C, Stellos K, Stransky E et al. Decreased plasma levels of granulocyte-colony stimulating factor (G-CSF) in patients with early Alzheimer's disease. J Alzheimers Dis 2009; 17: 115123.
  • 38
    Maler JM, Spitzer P, Lewczuk P et al. Decreased circulating CD34+ stem cells in early Alzheimer's disease: Evidence for a deficient hematopoietic brain support? Mol Psychiatry 2006; 11: 11131115.
  • 39
    Sanchez-Ramos J, Song S, Cao C et al. The potential of hematopoietic growth factors for treatment of Alzheimer's disease: A mini-review. BMC Neurosci 2008; 9( suppl 2): S3.
  • 40
    Hasselblatt M, Jeibmann A, Riesmeier B et al. Granulocyte-colony stimulating factor (G-CSF) and G-CSF receptor expression in human ischemic stroke. Acta Neuropathol 2007; 113: 4551.
  • 41
    Wirenfeldt M, Dissing-Olesen L, Anne Babcock A et al. Population control of resident and immigrant microglia by mitosis and apoptosis. J Neurosci 2009; 29: 13191330.
  • 42
    Priller J, Flügel A, Wehner T et al. Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment. Nat Med 2001; 7: 13561361.
  • 43
    Mildner A, Schmidt H, Nitsche M et al. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci 2007; 10: 15441553.
  • 44
    Turrin NP, Plante MM, Lessard M et al. Irradiation does not compromise or exacerbate the innate immune response in the brains of mice that were transplanted with bone marrow stem cells. Stem Cells 2007; 25: 31653172.
  • 45
    Schlachetzki JC, Hull M. Microglial activation in Alzheimer's disease. Curr Alzheimer Res 2009; 6: 554563.
  • 46
    Flanary BE, Sammons NW, Nguyen C et al. Evidence that aging and amyloid promote microglial cell senescence. Rejuvenation Res 2007; 10: 6174.
  • 47
    Davoust N, Vuaillat C, Androdias G et al. From bone marrow to microglia: Barriers and avenues. Trends Immunol 2008; 29: 227234.
  • 48
    Rabinovici GD, Jagust WJ. Amyloid imaging in aging and dementia: Testing the amyloid hypothesis in vivo. Behav Neurol 2009; 21: 117128.
  • 49
    Jack CR, Jr, Lowe VJ, Weigand SD et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease. Brain 2009; 132: 13551365.
  • 50
    Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Lancet 2001; 357: 169175.
  • 51
    Engler H, Forsberg A, Almkvist O et al. Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain 2006; 129: 28562866.
  • 52
    Holmes C, Boche D, Wilkinson D et al. Long-term effects of Abeta42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebo-controlled phase I trial. Lancet 2008; 372: 216223.
  • 53
    Wirths O, Breyhan H, Marcello A et al. Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease. Neurobiol Aging 2010; 31: 747757.
  • 54
    He P, Zhong Z, Lindholm K et al. Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice. J Cell Biol 2007; 178: 829841.
  • 55
    Chavant F, Deguil J, Pain S et al. Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in a mouse model of Alzheimer's disease. J Pharmacol Exp Ther 2010; 332: 505514.
  • 56
    Nolan Y, Maher FO, Martin DS et al. Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus. J Biol Chem 2005; 280: 93549362.
  • 57
    Minghetti L, Ajmone-Cat MA, De Berardinis MA et al. Microglial activation in chronic neurodegenerative diseases: Roles of apoptotic neurons and chronic stimulation. Brain Res Brain Res Rev 2005; 48: 251256.
  • 58
    Jimenez S, Baglietto-Vargas D, Caballero C et al. Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic. J Neurosci 2008; 28: 1165011661.
  • 59
    Verret L, Jankowsky JL, Xu GM et al. Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci 2007; 27: 67716780.
  • 60
    Rodriguez JJ, Jones VC, Tabuchi M et al. Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PLoS One 2008; 3: e2935.
  • 61
    Imitola J, Raddassi K, Park KI et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 2004; 101: 1811718122.
  • 62
    Whitney NP, Eidem TM, Peng H et al. Inflammation mediates varying effects in neurogenesis: Relevance to the pathogenesis of brain injury and neurodegenerative disorders. J Neurochem 2009; 108: 13431359.
  • 63
    Rock RB, Gekker G, Hu S et al. Role of microglia in central nervous system infections. Clin Microbiol Rev 2004; 17: 942964, table of contents.