Translational and Clinical Research

You have full text access to this OnlineOpen article

Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential†‡§

  1. Yang Liu1,2,¶,
  2. Xiaohua Jiang1,3,¶,
  3. Xiaohu Zhang1,¶,
  4. Rui Chen1,
  5. Tingting Sun1,
  6. Kin Lam Fok1,
  7. Jianda Dong1,
  8. Lai Ling Tsang1,
  9. Shaoqiong Yi4,
  10. Yechun Ruan1,
  11. Jinghui Guo1,
  12. Mei Kuen Yu1,
  13. Yuemin Tian1,
  14. Yiu Wa Chung1,
  15. Mo Yang5,
  16. Wenming Xu1,6,
  17. Chin Man Chung1,
  18. Tingyu Li2,‖,††,*,
  19. Hsiao Chang Chan1,3,‡‡,††,*

Article first published online: 16 NOV 2011

DOI: 10.1002/stem.764

Issue

STEM CELLS

STEM CELLS

Volume 29, Issue 12, pages 2077–2089, December 2011

Additional Information

How to Cite

Liu, Y., Jiang, X., Zhang, X., Chen, R., Sun, T., Fok, K. L., Dong, J., Tsang, L. L., Yi, S., Ruan, Y., Guo, J., Yu, M. K., Tian, Y., Chung, Y. W., Yang, M., Xu, W., Chung, C. M., Li, T. and Chan, H. C. (2011), Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential. STEM CELLS, 29: 2077–2089. doi: 10.1002/stem.764

Author Information

  1. 1

    Epithelial Cell Biology Research Center, School of Biomedical Sciences, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong

  2. 2

    Children's Hospital, Chongqing Medical University, Chongqing, People's Republic of China

  3. 3

    Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University-the Chinese University of Hong Kong, Guangzhou, People's Republic of China

  4. 4

    Department of Applied Molecular Biology, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, People's Republic of China

  5. 5

    Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China

  6. 6

    Sichuan University–the Chinese University of Hong Kong Joint Laboratory for Reproductive Medicine, Key Laboratory of Obstetric, Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Women's and Children's Hospital, Sichuan University, Chengdu, People's Republic of China

  1. Contributed equally as first authors.

  2. ‖

    Telephone: 8623-63628660; Fax: 8623-63626904

  3. ‡‡

    Telephone: 852-26961105; Fax: 852-26037155

  4. ††

    Contributed equally as corresponding authors.

*Children's Hospital, Chongqing Medical University, Chongqing, China

  1. †

    Author contributions: Y.L. and X.Z.: collection and/or assembly of data, data analysis and interpretation, manuscript writing, and final approval of manuscript; X.J.: design, collection and/or assembly of data, data analysis and interpretation, manuscript writing, and final approval of manuscript; R.C., T.S., K.L.F., J.D., L.L.T., S.Y., Y.R., J.G., M.K.Y., Y.T., and W.X.: collection and/or assembly of data, data analysis and interpretation, and final approval of manuscript; Y.W.C.: collection and/or assembly of data, data analysis and interpretation, administrative support, and final approval of manuscript; M.Y.: data analysis and interpretation, provision of study material, and final approval of manuscript; C.M.C.: collection and/or assembly of data and data analysis and interpretation, T.L.: conception and design, financial support, provision of study material, data analysis and interpretation, and final approval of manuscript; H.C.C: conception and design, financial support, provision of study material, data analysis and interpretation, manuscript writing, and final approval of manuscript.

  2. ‡

    Disclosure of potential conflicts of interest is found at the end of this article.

  3. §

    First published online in STEM CELLSEXPRESS November 3, 2011.

  4. Contributed equally as first authors.

  5. ‖

    Telephone: 8623-63628660; Fax: 8623-63626904

  6. ‡‡

    Telephone: 852-26961105; Fax: 852-26037155

  7. ††

    Contributed equally as corresponding authors.

Publication History

  1. Issue published online: 16 NOV 2011
  2. Article first published online: 16 NOV 2011
  3. Accepted manuscript online: 3 NOV 2011 08:50AM EST
  4. Manuscript Accepted: 27 SEP 2011
  5. Manuscript Received: 25 JAN 2011

Funded by

  • Focused Investment Scheme and Li Ka Shing Institute of Health Sciences of the Chinese University of Hong Kong
  • Morningside Foundation
  • National Natural Science Foundation of China (. Grant Numbers: 30830106, 30872670, 81100475
  • National Basic Research Program of China. Grant Number: 012CB944900
  • Fundamental Research Funds for the Central Universities (Jinan University)
  • Chinese University of Hong Kong. Grant Numbers: 2009.1.071, 2010.1.016
  • Hong Kong University Grants Committee. Grant Numbers: GRF2010/2011, CUHK466710
  • NSFC grant. Grant Number: 31140034

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (5211K)

Cited in:

CrossRef

This article has been cited by:

  1. 1
    Andre W. Phillips, Michael V. Johnston, Ali Fatemi, The Potential for Cell-Based Therapy in Perinatal Brain Injuries, Translational Stroke Research, 2013, 4, 2, 137

    CrossRef

  2. 2
    BiotecVisions 2012, February, Biotechnology Journal, 2012, 7, 2
    Direct Link:
View Full Article with Supporting Information (HTML) Get PDF (5211K)