STEM CELLS

Cover image for Vol. 33 Issue 9

September 2015

Volume 33, Issue 9

Pages 2643–2886

  1. Embryonic Stem Cells/Induced Pluripotent Stem Cells

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. You have free access to this content
      Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells (pages 2643–2651)

      Chunbo Yang, Jumana Al-Aama, Miodrag Stojkovic, Bernard Keavney, Andrew Trafford, Majlinda Lako and Lyle Armstrong

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2070

  2. Cancer Stem Cells

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
  3. Embryonic Stem Cells/Induced Pluripotent Stem Cells

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. CD38 Is Required for Neural Differentiation of Mouse Embryonic Stem Cells by Modulating Reactive Oxygen Species (pages 2664–2673)

      Wenjie Wei, Yingying Lu, Baixia Hao, Kehui Zhang, Qian Wang, Andrew L. Miller, Liang-Ren Zhang, Li-He Zhang and Jianbo Yue

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2057

    2. Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells (pages 2686–2698)

      Galbha Duggal, Sharat Warrier, Sabitri Ghimire, Dorien Broekaert, Margot Van der Jeught, Sylvie Lierman, Tom Deroo, Luc Peelman, Ann Van Soom, Ria Cornelissen, Björn Menten, Pieter Mestdagh, Jo Vandesompele, Matthias Roost, Roderick C. Slieker, Bastiaan T. Heijmans, Dieter Deforce, Petra De Sutter, Susana Chuva De Sousa Lopes and Björn Heindryckx

      Article first published online: 24 JUN 2015 | DOI: 10.1002/stem.2071

      Thumbnail image of graphical abstract

      Different Shades of Naïve Pluripotency in Human Embryonic Stem Cells.

    3. Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency (pages 2699–2711)

      Hyunsoo Kim, Hyonchol Jang, Tae Wan Kim, Byung-Hee Kang, Sang Eun Lee, Yoon Kyung Jeon, Doo Hyun Chung, Jinmi Choi, Jihoon Shin, Eun-Jung Cho and Hong-Duk Youn

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2073

      Thumbnail image of graphical abstract

      Overexpression of Hk2 and Pkm2 enables ESCs to maintain high glycolytic flux. Sustaining high glycolytic flux during differentiation prevents ESCs from complete differentiation and allowing them to retain self-renewal potential or pluripotency.

  4. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells (pages 2712–2725)

      Claire M. Mulvey, Christian Schröter, Laurent Gatto, Duygu Dikicioglu, Isik Baris Fidaner, Andy Christoforou, Michael J. Deery, Lily T. Y. Cho, Kathy K. Niakan, Alfonso Martinez-Arias and Kathryn S. Lilley

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2067

      Thumbnail image of graphical abstract

      Here we report a time-resolved, global proteomic map of cellular change during the directed differentiation of mouse ES cells into extraembryonic endoderm-like cells induced by forced GATA factor expression. This study reveals that transition from the pluripotent to the differentiated state is accompanied by the downregulation of chromatin-modifying enzymes and cell-cell adhesion molecules, and by the successive upregulation of proteins involved in extracellular matrix biogenesis, membrane trafficking and the tricarboxylic acid cycle, as well as an increase in MAPK signaling.

  5. Translational and Clinical Research

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy (pages 2726–2737)

      Birgitta M. Gleeson, Kenneth Martin, Mohammed T. Ali, Arun H. S. Kumar, M. Gopala-Krishnan Pillai, Sujith P. G. Kumar, John F. O'Sullivan, Derek Whelan, Alessia Stocca, Wisam Khider, Frank P. Barry, Timothy O'Brien and Noel M. Caplice

      Article first published online: 4 JUN 2015 | DOI: 10.1002/stem.2050

    2. p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion (pages 2738–2747)

      Xiaomei Qi, Ning Yin, Shao Ma, Adrienne Lepp, Jun Tang, Weiqing Jing, Bryon Johnson, Michael B. Dwinell, Christopher R. Chitambar and Guan Chen

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2068

  6. Regenerative Medicine

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior (pages 2748–2761)

      Sylwia Bobis-Wozowicz, Katarzyna Kmiotek, Malgorzata Sekula, Sylwia Kedracka-Krok, Elzbieta Kamycka, Marta Adamiak, Urszula Jankowska, Anna Madetko-Talowska, Michal Sarna, Miroslaw Bik-Multanowski, Jacek Kolcz, Dariusz Boruczkowski, Zbigniew Madeja, Buddhadeb Dawn and Ewa K. Zuba-Surma

      Article first published online: 24 JUN 2015 | DOI: 10.1002/stem.2078

  7. Tissue-Specific Stem Cells

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived But Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells (pages 2773–2784)

      Ben P. Hung, Daphne L. Hutton, Kristen L. Kozielski, Corey J. Bishop, Bilal Naved, Jordan J. Green, Arnold I. Caplan, Jeffrey M. Gimble, Amir H. Dorafshar and Warren L. Grayson

      Article first published online: 26 JUN 2015 | DOI: 10.1002/stem.2060

    2. You have full text access to this OnlineOpen article
    3. CD49f Acts as an Inflammation Sensor to Regulate Differentiation, Adhesion, and Migration of Human Mesenchymal Stem Cells (pages 2798–2810)

      Zhigang Yang, Ping Dong, Xin Fu, Qiuchen Li, Shize Ma, Dongying Wu, Ning Kang, Xia Liu, Li Yan and Ran Xiao

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2063

    4. A Niche for GFRα1-Positive Spermatogonia in the Terminal Segments of the Seminiferous Tubules in Hamster Testes (pages 2811–2824)

      Yoshimi Aiyama, Naoki Tsunekawa, Kasane Kishi, Miyuri Kawasumi, Hitomi Suzuki, Masami Kanai-Azuma, Masamichi Kurohmaru and Yoshiakira Kanai

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2065

    5. The NFKB Inducing Kinase Modulates Hematopoiesis During Stress (pages 2825–2837)

      África González-Murillo, Lucía Fernández, Sara Baena, Gustavo J. Melen, Rebeca Sánchez, Carmen Sánchez-Valdepeñas, José C. Segovia, Hsiou-Chi Liou, Roland Schmid, Luís Madero, Manuel Fresno and Manuel Ramírez

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2066

    6. EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance (pages 2838–2849)

      Thao M. Nguyen, Agnieszka Arthur, Romana Panagopoulos, Sharon Paton, John D. Hayball, Andrew C.W. Zannettino, Louise E. Purton, Koichi Matsuo and Stan Gronthos

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2069

    7. You have free access to this content
      Interleukin-17A-Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function (pages 2850–2863)

      Kisha Nandini Sivanathan, Darling M. Rojas-Canales, Christopher M. Hope, Ravi Krishnan, Robert P. Carroll, Stan Gronthos, Shane T. Grey and Patrick T. Coates

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2075

    8. You have full text access to this OnlineOpen article
      Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord (pages 2864–2876)

      Laura F. Corns, Lucy Atkinson, Jill Daniel, Ian J. Edwards, Lauryn New, Jim Deuchars and Susan A. Deuchars

      Article first published online: 26 JUN 2015 | DOI: 10.1002/stem.2077

  8. Translational and Clinical Research

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. Brief Report: Human Mesenchymal Stem-Like Cells Facilitate Floating Tumorigenic Cell Growth via Glutamine-Ammonium Cycle (pages 2877–2884)

      Ke Tang, Liang Hu, Jingwei Ma, Huafeng Zhang, Yi Zhang, Yong Li, Ruihua Ma, Shunqun Luo, Dongbo Liu, Guoxian Long, Mei Han, Shunfang Liu, Anping Song, Meizhu Shen, Guoqing Hu and Bo Huang

      Article first published online: 23 JUN 2015 | DOI: 10.1002/stem.2076

  9. Corrigendum

    1. Top of page
    2. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    3. Cancer Stem Cells
    4. Embryonic Stem Cells/Induced Pluripotent Stem Cells
    5. Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
    6. Translational and Clinical Research
    7. Regenerative Medicine
    8. Tissue-Specific Stem Cells
    9. Translational and Clinical Research
    10. Corrigendum
    1. You have free access to this content

SEARCH

SEARCH BY CITATION