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Olfactory tubercle neurons exhibit slow-phasic firing patterns during cocaine self-administration

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Abstract

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Electrophysiological recordings from the Olfactory Tubercle (OT) of rats trained to self-administer cocaine were analyzed for distinct firing patterns. Observation revealed that neurons demonstrated changes in firing correlated with the calculated fluctuating levels of cocaine. These are the first electrophysiological data suggesting a role for the OT in drug self-administration.

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