Within the current methodological debate, notions successful in the natural sciences are rallied by social sciences researchers to support their own methodological approaches. However, problems of understanding the physical principles have often clouded the issue. One such notion under discussion is Heisenberg's uncertainty principle and the derivative notions of indeterminacy, uncertainty, precision, and observer–observed interaction. This article discusses these notions and their applications to social science research. Implications are drawn for research in science education.