Biological olfaction is a powerful system enabling acquisition and processing of various chemical information from environment. Vast significance of the sense of smell is reflected in attempts to create instrumental techniques mimicking the biological system—artificial/machine olfaction. Following the biological systems, the artificial olfaction relies on arrays of gas sensors with broad specificities to odorants. Arguably, among available gas-sensing technologies, the most suitable choices for artificial olfaction are acoustic wave sensors, including quartz crystal microbalance (QCM) gas/odor sensors. The short review herein presents basic information on organization and principles of biological and artificial olfaction systems as well as several methods for fabrication of biomimetic or bioinspired (QCM) sensors for artificial olfaction. Copyright © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.