Recently, renewable energy technologies such as wind turbine generators and photovoltaic (PV) systems have been introduced as distributed generations (DGs). Connections of a large amount of distributed generations may cause voltage deviation beyond the statutory range in distribution systems. A reactive power control of DGs can be a solution of this problem, and it also has a possibility to reduce distribution loss. In this paper, we propose a control methodology of voltage profile in a distribution system using reactive power control of inverters interfaced with DGs and tap changing transformers. In the proposed method, a one-day schedule of voltage references for the control devices are determined by an optimization technique based on predicted values of load demand and PV power generation. Reactive power control of interfaced inverters is implemented within the inverter capacity without reducing active power output. The proposed method accomplishes voltage regulation within the acceptable range and reduction of distribution loss. The effectiveness of the proposed method is confirmed by simulations. Copyright © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.