Second-trimester uterine artery Doppler and spontaneous preterm delivery
Article first published online: 4 AUG 2004
Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.
Ultrasound in Obstetrics & Gynecology
Volume 24, Issue 4, pages 435–439, September 2004
How to Cite
Cobian-Sanchez, F., Prefumo, F., Bhide, A. and Thilaganathan, B. (2004), Second-trimester uterine artery Doppler and spontaneous preterm delivery. Ultrasound Obstet Gynecol, 24: 435–439. doi: 10.1002/uog.1116
- Issue published online: 21 AUG 2004
- Article first published online: 4 AUG 2004
- Manuscript Accepted: 18 MAR 2004
- preterm delivery;
- second trimester;
- uterine arteries
To assess the relationship between second-trimester uterine artery (UtA) Doppler measurements and spontaneous preterm delivery.
This was a retrospective analysis of UtA Doppler findings at 18–23 weeks' gestation in 234 singleton pregnancies with spontaneous preterm labor and 5472 pregnancies delivered at term. Cases with fetal chromosomal or structural abnormalities, pre-eclampsia, small-for-gestational-age (SGA) fetuses, concurrent maternal disease, cervical cerclage or history of cone biopsy were excluded.
UtA mean resistance index (RI) and number of protodiastolic notches were not significantly different in the spontaneous preterm labor group compared to the normal group. The 62 preterm deliveries not preceded by spontaneous preterm premature rupture of membranes (PPROM) showed a significantly higher RI and prevalence of bilateral notches than cases of preterm deliveries preceded by PPROM (n = 172). However, this difference was not confirmed in a logistic regression model.
Despite pathological evidence suggesting that defective placentation is associated with spontaneous preterm delivery, second-trimester UtA resistance, as assessed by Doppler ultrasound investigation, is not different in pregnancies subsequently complicated by preterm labor compared to pregnancies delivered at term. Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.