Role of cerebroplacental ratio for fetal assessment in prolonged pregnancy
Article first published online: 7 JUL 2013
Copyright © 2012 ISUOG. Published by John Wiley & Sons Ltd.
Ultrasound in Obstetrics & Gynecology
Volume 42, Issue 2, pages 196–200, August 2013
How to Cite
D'Antonio, F., Patel, D., Chandrasekharan, N., Thilaganathan, B. and Bhide, A. (2013), Role of cerebroplacental ratio for fetal assessment in prolonged pregnancy. Ultrasound Obstet Gynecol, 42: 196–200. doi: 10.1002/uog.12357
- Issue published online: 26 JUL 2013
- Article first published online: 7 JUL 2013
- Accepted manuscript online: 13 DEC 2012 06:57AM EST
- Manuscript Accepted: 13 NOV 2012
- fetal Doppler;
- prolonged pregnancy
The aim of this study was to assess the role of the cerebroplacental ratio (CPR), i.e. the ratio between the middle cerebral artery and umbilical artery pulsatility indices, in detecting fetal compromise in prolonged pregnancy.
Women attending a dedicated postdates clinic at 41 weeks' gestation were recruited for the study and CPR was calculated at 41+3 weeks. Induction of labor was offered at 42 weeks to those women still undelivered. Unfavorable outcome was defined as cord arterial pH < 7.15 with a base deficit of > 11 mM/L or operative delivery for abnormal intrapartum fetal electrocardiogram ST-segment analysis. The 5th centiles of the CPR, obtained from published reference ranges (0.90) and from our population (0.98), were used as lower cut-off values.
Three hundred and twenty women who reached a gestational age of over 41 weeks were eligible for inclusion in the study. The median gestational age at delivery was 294 (range, 289–300) days. Unfavorable outcome was observed in 58/320 pregnancies. There was no significant difference in the proportion of unfavorable outcomes between the two groups defined using either CPR cut-off value (both P > 0.05).
CPR is not predictive of unfavorable outcome in women with pregnancies lasting more than 41 weeks. Copyright © 2012 ISUOG. Published by John Wiley & Sons Ltd.