Weight estimation by three-dimensional ultrasound imaging in the small fetus
Article first published online: 29 JUL 2008
Copyright © 2008 ISUOG. Published by John Wiley & Sons, Ltd.
Ultrasound in Obstetrics & Gynecology
Volume 32, Issue 2, pages 168–175, August 2008
How to Cite
Schild, R. L., Maringa, M., Siemer, J., Meurer, B., Hart, N., Goecke, T. W., Schmid, M., Hothorn, T. and Hansmann, M. E. (2008), Weight estimation by three-dimensional ultrasound imaging in the small fetus. Ultrasound Obstet Gynecol, 32: 168–175. doi: 10.1002/uog.6111
- Issue published online: 29 JUL 2008
- Article first published online: 29 JUL 2008
- Manuscript Accepted: 21 APR 2008
- Deutsche Forschungsgemeinschaft. Grant Number: (SCHI/552–1)
- 3D ultrasound;
- fetal weight;
- small fetus
To improve birth weight estimation in fetuses weighing ⩽ 1600 g at birth by deriving a new formula including measurements obtained using three-dimensional (3D) sonography.
In a prospective cohort study, biometric data of 150 singleton fetuses weighing ⩽ 1600 g at birth were obtained by sonographic examination within 1 week before delivery. Exclusion criteria were multiple pregnancy, intrauterine death as well as major structural or chromosomal anomalies. A new formula was derived using our data, and was then compared with currently available equations for estimating weight in the preterm fetus.
Different statistical estimation strategies were pursued. Gradient boosting with component- wise smoothing splines achieved the best results. The resulting new formula (estimated fetal weight = 656.41 + 1.8321 × volABDO + 31.1981 × HC + 5.7787 × volFEM + 73.5214 × FL + 8.3009 × AC − 449.8863 × BPD + 32.5340 × BPD2, where volABDO is abdominal volume determined by 3D volumetry, HC is head circumference, volFEM is thigh volume determined by 3D volumetry, FL is femur length and BPD is biparietal diameter) proved to be superior to established equations in terms of mean squared prediction errors, signed percentage errors and absolute percentage errors.
Our new formula is relatively easy to use and needs no adjustment to weight percentiles or to fetal lie. In fetuses weighing ⩽ 1600 g at birth it is superior to weight estimation by traditional formulae using two-dimensional measurements. Copyright © 2008 ISUOG. Published by John Wiley & Sons, Ltd.